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Most cancer cells displayed weak to moderate cytoplasmic and nuclear positivity. Strong staining was observed in a few urothelial cancers while gliomas and cervical cancers were negative in several cases.
GENE INFORMATION
Gene name
KDM8 (HGNC Symbol)
Synonyms
FLJ13798, JMJD5
Description
Lysine (K)-specific demethylase 8 (HGNC Symbol)
Entrez gene summary
This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]