Tissue expression of PSD3 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PSD3
Gene description	Pleckstrin and Sec7 domain containing 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	11
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (cerebral cortex)
GTEx:	Tissue enhanced (cerebellum)
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebellum)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	PSD3 (HGNC Symbol)
Synonyms	DKFZp761K1423, EFA6D, EFA6R, HCA67, KIAA0942
Description	Pleckstrin and Sec7 domain containing 3 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	p22
Chromosome location (bp)	18527301 - 19084730
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156011 (version 83.38)
Entrez gene	23362
UniProt	Q9NYI0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NYI0
Antibodypedia	PSD3 antibodies

PROTEIN BROWSER

PSD3-001	PSD3-002	PSD3-003	PSD3-006	PSD3-010	PSD3-011	PSD3-017	PSD3-019	PSD3-201	PSD3-202	PSD3-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PSD3-001 ENSP00000324127 ENST00000327040	Q9NYI0 [Direct mapping] PH and SEC7 domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0014069 [postsynaptic density] GO:0016020 [membrane] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0032012 [regulation of ARF protein signal transduction] GO:0043547 [positive regulation of GTPase activity] GO:0045211 [postsynaptic membrane] Show all	1047 aa 115.9 kDa	No	0
PSD3-002 ENSP00000430640 ENST00000523619	E5RJ29 [Direct mapping] PH and SEC7 domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0032012 [regulation of ARF protein signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	982 aa 109 kDa	No	0
PSD3-003 ENSP00000286485 ENST00000286485	Q9NYI0 [Direct mapping] PH and SEC7 domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0014069 [postsynaptic density] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0032012 [regulation of ARF protein signal transduction] GO:0043547 [positive regulation of GTPase activity] GO:0045211 [postsynaptic membrane] Show all	513 aa 58.1 kDa	No	0
PSD3-006 ENSP00000393228 ENST00000428502	B4DKF8 [Direct mapping] PH and SEC7 domain-containing protein 3; Pleckstrin and Sec7 domain containing 3, isoform CRA_a; cDNA FLJ54694, highly similar to Pleckstrin and Sec7 domain-containing protein3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0005543 [phospholipid binding] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0043547 [positive regulation of GTPase activity] Show all	376 aa 42.5 kDa	No	0
PSD3-010 ENSP00000429069 ENST00000519851	E5RJE4 [Direct mapping] PH and SEC7 domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0032012 [regulation of ARF protein signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	165 aa 18.9 kDa	No	0
PSD3-011 ENSP00000427897 ENST00000521027	H0YAQ7 [Direct mapping] PH and SEC7 domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0032012 [regulation of ARF protein signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	119 aa 13.2 kDa	No	0
PSD3-017 ENSP00000430744 ENST00000520858	H0YC20 [Direct mapping] PH and SEC7 domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0032012 [regulation of ARF protein signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	165 aa 19 kDa	No	0
PSD3-019 ENSP00000428405 ENST00000521475	E5RIH3 [Direct mapping] PH and SEC7 domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0043547 [positive regulation of GTPase activity] Show all	142 aa 15.4 kDa	No	0
PSD3-201 ENSP00000401704 ENST00000440756	Q9NYI0 [Direct mapping] PH and SEC7 domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0014069 [postsynaptic density] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0032012 [regulation of ARF protein signal transduction] GO:0043547 [positive regulation of GTPase activity] GO:0045211 [postsynaptic membrane] Show all	1048 aa 116 kDa	No	0
PSD3-202 ENSP00000480930 ENST00000614430	A0A087WXD8 [Direct mapping] PH and SEC7 domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0043547 [positive regulation of GTPase activity] Show all	269 aa 30.5 kDa	No	0
PSD3-203 ENSP00000484565 ENST00000615573	A0A087X1Z0 [Direct mapping] PH and SEC7 domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005086 [ARF guanyl-nucleotide exchange factor activity] GO:0030054 [cell junction] GO:0030182 [neuron differentiation] GO:0043547 [positive regulation of GTPase activity] Show all	269 aa 30.5 kDa	No	0