Cell atlas - ART3 - The Human Protein Atlas

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ART3

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ART3
Gene description	ADP-ribosyltransferase 3
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins
Predicted localization	Intracellular,Membrane,Secreted
Number of transcripts	8
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (NTERA-2, SK-MEL-30, NB-4)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (NTERA-2, SK-MEL-30, NB-4) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ART3
Synonyms
Description	ADP-ribosyltransferase 3 (HGNC Symbol)
Entrez gene summary	This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Chromosome	4
Cytoband	q21.1
Chromosome location (bp)	76011184 - 76112802
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156219 (version 83.38)
Entrez gene	419
UniProt	Q13508 (UniProt - Evidence at protein level)
neXtProt	NX_Q13508
Antibodypedia	ART3 antibodies

PROTEIN BROWSER

ART3-001	ART3-002	ART3-004	ART3-009	ART3-012	ART3-013	ART3-014	ART3-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ART3-001 ENSP00000348064 ENST00000355810	Q13508 [Direct mapping] Ecto-ADP-ribosyltransferase 3 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0003956 [NAD(P)+-protein-arginine ADP-ribosyltransferase activity] GO:0005887 [integral component of plasma membrane] GO:0006471 [protein ADP-ribosylation] GO:0031225 [anchored component of membrane] GO:0070062 [extracellular exosome] Show all	389 aa 43.9 kDa	Yes	1
ART3-002 ENSP00000304313 ENST00000349321	Q13508 [Direct mapping] Ecto-ADP-ribosyltransferase 3 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0003956 [NAD(P)+-protein-arginine ADP-ribosyltransferase activity] GO:0005887 [integral component of plasma membrane] GO:0006471 [protein ADP-ribosylation] GO:0031225 [anchored component of membrane] GO:0070062 [extracellular exosome] Show all	378 aa 42.7 kDa	Yes	1
ART3-004 ENSP00000343843 ENST00000341029	Q13508 [Direct mapping] Ecto-ADP-ribosyltransferase 3 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0003956 [NAD(P)+-protein-arginine ADP-ribosyltransferase activity] GO:0005887 [integral component of plasma membrane] GO:0006471 [protein ADP-ribosylation] GO:0031225 [anchored component of membrane] GO:0070062 [extracellular exosome] Show all	367 aa 41.5 kDa	Yes	1
ART3-009 ENSP00000422249 ENST00000511188	Q5J1K9 [Direct mapping] Ecto-ADP-ribosyltransferase 3; Mono-ADP-ribosyltransferase 3 variant Ia Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003956 [NAD(P)+-protein-arginine ADP-ribosyltransferase activity] GO:0006471 [protein ADP-ribosylation] Show all	117 aa 13.3 kDa	No	0
ART3-012 ENSP00000422287 ENST00000513122	E7ESB3 [Direct mapping] NAD(P)(+)--arginine ADP-ribosyltransferase Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003956 [NAD(P)+-protein-arginine ADP-ribosyltransferase activity] GO:0006471 [protein ADP-ribosylation] Show all	202 aa 23.2 kDa	Yes	0
ART3-013 ENSP00000421345 ENST00000513353	E9PGR5 [Direct mapping] Ecto-ADP-ribosyltransferase 3 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003956 [NAD(P)+-protein-arginine ADP-ribosyltransferase activity] GO:0006471 [protein ADP-ribosylation] Show all	107 aa 12.4 kDa	Yes	0
ART3-014 ENSP00000421431 ENST00000504914	E7EX61 [Direct mapping] Ecto-ADP-ribosyltransferase 3 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003956 [NAD(P)+-protein-arginine ADP-ribosyltransferase activity] GO:0006471 [protein ADP-ribosylation] Show all	129 aa 15 kDa	Yes	0
ART3-015 ENSP00000425327 ENST00000510423	E7ER42 [Direct mapping] NAD(P)(+)--arginine ADP-ribosyltransferase Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003956 [NAD(P)+-protein-arginine ADP-ribosyltransferase activity] GO:0006471 [protein ADP-ribosylation] Show all	175 aa 20.2 kDa	Yes	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.