Tissue expression of SAMD8 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	SAMD8
Gene description	Sterile alpha motif domain containing 8
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	SAMD8 (HGNC Symbol)
Synonyms	FLJ25082, SMSr
Description	Sterile alpha motif domain containing 8 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q22.2
Chromosome location (bp)	75099586 - 75182123
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156671 (version 83.38)
Entrez gene	142891
UniProt	Q96LT4 (UniProt - Evidence at protein level)
neXtProt	NX_Q96LT4
Antibodypedia	SAMD8 antibodies

PROTEIN BROWSER

SAMD8-001	SAMD8-002	SAMD8-003	SAMD8-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SAMD8-001 ENSP00000361772 ENST00000372687	Q96LT4 [Direct mapping] Sphingomyelin synthase-related protein 1 V9HVY4 [Target identity:100%; Query identity:100%] Epididymis luminal protein 177; Sterile alpha motif domain containing 8, isoform CRA_c Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0006686 [sphingomyelin biosynthetic process] GO:0016021 [integral component of membrane] GO:0016740 [transferase activity] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0046513 [ceramide biosynthetic process] GO:2000303 [regulation of ceramide biosynthetic process] Show all	326 aa 37.6 kDa	No	4
SAMD8-002 ENSP00000361775 ENST00000372690	A0A0A0MRR2 [Direct mapping] Sphingomyelin synthase-related protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	478 aa 54.8 kDa	No	6
SAMD8-003 ENSP00000391799 ENST00000447533	Q5JSC9 [Direct mapping] Sphingomyelin synthase-related protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	254 aa 29.5 kDa	No	3
SAMD8-201 ENSP00000438042 ENST00000542569	Q96LT4 [Direct mapping] Sphingomyelin synthase-related protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0006686 [sphingomyelin biosynthetic process] GO:0016021 [integral component of membrane] GO:0016740 [transferase activity] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0046513 [ceramide biosynthetic process] GO:2000303 [regulation of ceramide biosynthetic process] Show all	415 aa 48.3 kDa	No	6