Expression of UNC5D in cancer - Summary

CANCER ATLAS

Gene description

Unc-5 netrin receptor D

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA042940

GENE INFORMATION
Gene name	UNC5D (HGNC Symbol)
Synonyms	KIAA1777, Unc5h4
Description	Unc-5 netrin receptor D (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	p12
Chromosome location (bp)	35235457 - 35796550
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156687 (version 83.38)
Entrez gene	137970
UniProt	Q6UXZ4 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UXZ4
Antibodypedia	UNC5D antibodies

PROTEIN BROWSER

UNC5D-001	UNC5D-002	UNC5D-003	UNC5D-004	UNC5D-005	UNC5D-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UNC5D-001 ENSP00000394303 ENST00000453357	Q6UXZ4 [Direct mapping] Netrin receptor UNC5D Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Show all	GO:0005515 [protein binding] GO:0006915 [apoptotic process] GO:0007165 [signal transduction] GO:0007411 [axon guidance] GO:0016021 [integral component of membrane] GO:0098609 [cell-cell adhesion] Show all	948 aa 105.5 kDa	Yes	1
UNC5D-002 ENSP00000385143 ENST00000404895	Q6UXZ4 [Direct mapping] Netrin receptor UNC5D Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0006915 [apoptotic process] GO:0007165 [signal transduction] GO:0007411 [axon guidance] GO:0009986 [cell surface] GO:0016021 [integral component of membrane] GO:0021859 [pyramidal neuron differentiation] GO:0098609 [cell-cell adhesion] GO:2001222 [regulation of neuron migration] Show all	953 aa 105.9 kDa	Yes	1
UNC5D-003 ENSP00000287272 ENST00000287272	H7BXJ2 [Direct mapping] Netrin receptor UNC5D Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0007165 [signal transduction] GO:0016021 [integral component of membrane] Show all	884 aa 98.3 kDa	Yes	1
UNC5D-004 ENSP00000412652 ENST00000416672	C9J2B6 [Direct mapping] Netrin receptor UNC5D Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0007165 [signal transduction] GO:0016021 [integral component of membrane] Show all	958 aa 106.6 kDa	Yes	1
UNC5D-005 ENSP00000392739 ENST00000420357	C9J1I0 [Direct mapping] Netrin receptor UNC5D Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0007165 [signal transduction] GO:0016021 [integral component of membrane] Show all	886 aa 98.5 kDa	Yes	1
UNC5D-007 ENSP00000397211 ENST00000449677	E9PDS8 [Direct mapping] Netrin receptor UNC5D Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0007165 [signal transduction] Show all	529 aa 59.4 kDa	No	0