Expression of BRPF1 in cancer - Summary

CANCER ATLAS

Gene description

Bromodomain and PHD finger containing, 1

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA003359

GENE INFORMATION
Gene name	BRPF1 (HGNC Symbol)
Synonyms	BR140
Description	Bromodomain and PHD finger containing, 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is expressed ubiquitously and at the highest level in testes and spermatogonia. The protein is localized within nuclei, and it is very similar in structure to two zinc finger proteins, AF10 and AF17. It is suggested that these proteins form a family of regulatory proteins. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	3
Cytoband	p25.3
Chromosome location (bp)	9731729 - 9748018
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156983 (version 83.38)
Entrez gene	7862
UniProt	P55201 (UniProt - Evidence at protein level)
neXtProt	NX_P55201
Antibodypedia	BRPF1 antibodies

PROTEIN BROWSER

BRPF1-001	BRPF1-002	BRPF1-003	BRPF1-004	BRPF1-005	BRPF1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BRPF1-001 ENSP00000373340 ENST00000383829	P55201 [Direct mapping] Peregrin Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0043966 [histone H3 acetylation] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0070776 [MOZ/MORF histone acetyltransferase complex] Show all	1220 aa 138.2 kDa	No	0
BRPF1-002 ENSP00000402485 ENST00000433861	P55201 [Direct mapping] Peregrin Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0043966 [histone H3 acetylation] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0070776 [MOZ/MORF histone acetyltransferase complex] Show all	1119 aa 127.4 kDa	No	0
BRPF1-003 ENSP00000398863 ENST00000424362	P55201 [Direct mapping] Peregrin Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0043966 [histone H3 acetylation] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0070776 [MOZ/MORF histone acetyltransferase complex] Show all	1213 aa 137.4 kDa	No	0
BRPF1-004 ENSP00000410210 ENST00000457855	P55201 [Direct mapping] Peregrin Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0043966 [histone H3 acetylation] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0070776 [MOZ/MORF histone acetyltransferase complex] Show all	1214 aa 137.5 kDa	No	0
BRPF1-005 ENSP00000416728 ENST00000420291	C9JDK5 [Direct mapping] Peregrin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0046872 [metal ion binding] Show all	100 aa 11.6 kDa	No	0
BRPF1-006 ENSP00000404235 ENST00000426583	C9JHC0 [Direct mapping] Peregrin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0046872 [metal ion binding] Show all	105 aa 12.1 kDa	No	0