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TATDN2

GENERAL INFORMATION

Gene name

 TATDN2

Gene description

 TatD DNase domain containing 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear expression in all tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA036822
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 TATDN2 (HGNC Symbol)

Synonyms

 KIAA0218

Description

 TatD DNase domain containing 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 p25.3

Chromosome location (bp)

 10248023 - 10281218

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000157014 (version 83.38)

Entrez gene

 9797

UniProt

 Q93075 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q93075

Antibodypedia

 TATDN2 antibodies

PROTEIN BROWSER
TATDN2-001
TATDN2-002
TATDN2-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TATDN2-001
ENSP00000287652
ENST00000287652
Q93075 [Direct mapping]
Putative deoxyribonuclease TATDN2
A0A024R2F3 [Target identity:100%; Query identity:100%]
TatD DNase domain containing 2, isoform CRA_a
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004536 [deoxyribonuclease activity]
GO:0005654 [nucleoplasm]
GO:0006308 [DNA catabolic process]
GO:0016888 [endodeoxyribonuclease activity, producing 5'-phosphomonoesters]
GO:0030968 [endoplasmic reticulum unfolded protein response]
GO:0036498 [IRE1-mediated unfolded protein response]
GO:0043229 [intracellular organelle]
GO:0044267 [cellular protein metabolic process]
GO:0046872 [metal ion binding]
GO:0090305 [nucleic acid phosphodiester bond hydrolysis]
Show all
 761 aa
85 kDa 		No 0
TATDN2-002
ENSP00000408736
ENST00000448281
Q93075 [Direct mapping]
Putative deoxyribonuclease TATDN2
A0A024R2F3 [Target identity:100%; Query identity:100%]
TatD DNase domain containing 2, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004536 [deoxyribonuclease activity]
GO:0005654 [nucleoplasm]
GO:0006308 [DNA catabolic process]
GO:0016888 [endodeoxyribonuclease activity, producing 5'-phosphomonoesters]
GO:0030968 [endoplasmic reticulum unfolded protein response]
GO:0036498 [IRE1-mediated unfolded protein response]
GO:0043229 [intracellular organelle]
GO:0044267 [cellular protein metabolic process]
GO:0046872 [metal ion binding]
GO:0090305 [nucleic acid phosphodiester bond hydrolysis]
Show all
 761 aa
85 kDa 		No 0
TATDN2-006
ENSP00000389896
ENST00000426850
H7BZJ2 [Direct mapping]
Putative deoxyribonuclease TATDN2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004536 [deoxyribonuclease activity]
GO:0006308 [DNA catabolic process]
GO:0016888 [endodeoxyribonuclease activity, producing 5'-phosphomonoesters]
GO:0043229 [intracellular organelle]
Show all
 182 aa
20.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.