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SEC13

CANCER ATLAS

Gene description

 SEC13 homolog, nuclear pore and COPII coat complex component

Protein class

 Predicted intracellular proteins, Transporters

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA035292

GENE INFORMATION

Gene name

 SEC13 (HGNC Symbol)

Synonyms

 D3S1231E, npp-20, SEC13L1, SEC13R

Description

 SEC13 homolog, nuclear pore and COPII coat complex component (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2008]

Chromosome

 3

Cytoband

 p25.3

Chromosome location (bp)

 10293131 - 10321178

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000157020 (version 83.38)

Entrez gene

 6396

UniProt

 P55735 (UniProt - Evidence at protein level)

neXtProt

 NX_P55735

Antibodypedia

 SEC13 antibodies

PROTEIN BROWSER
SEC13-001
SEC13-002
SEC13-003
SEC13-004
SEC13-005
SEC13-006
SEC13-007
SEC13-012
SEC13-019

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SEC13-001
ENSP00000312122
ENST00000350697
P55735 [Direct mapping]
Protein SEC13 homolog
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005829 [cytosol]
GO:0006886 [intracellular protein transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0007264 [small GTPase mediated signal transduction]
GO:0012507 [ER to Golgi transport vesicle membrane]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II]
GO:0031080 [nuclear pore outer ring]
GO:0032008 [positive regulation of TOR signaling]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0051028 [mRNA transport]
GO:0061024 [membrane organization]
GO:0061700 [GATOR2 complex]
GO:0070062 [extracellular exosome]
Show all
 322 aa
35.5 kDa 		No 0
SEC13-002
ENSP00000336566
ENST00000337354
A0A0C4DFR6 [Direct mapping]
Protein SEC13 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 325 aa
35.9 kDa 		No 0
SEC13-003
ENSP00000373312
ENST00000383801
P55735 [Direct mapping]
Protein SEC13 homolog
Show all
Transporters
   Transporter channels and pores
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005829 [cytosol]
GO:0006886 [intracellular protein transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0007264 [small GTPase mediated signal transduction]
GO:0012507 [ER to Golgi transport vesicle membrane]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II]
GO:0031080 [nuclear pore outer ring]
GO:0032008 [positive regulation of TOR signaling]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0051028 [mRNA transport]
GO:0061024 [membrane organization]
GO:0061700 [GATOR2 complex]
GO:0070062 [extracellular exosome]
Show all
 368 aa
40.7 kDa 		No 0
SEC13-004
ENSP00000380298
ENST00000397109
P55735 [Direct mapping]
Protein SEC13 homolog
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005829 [cytosol]
GO:0006886 [intracellular protein transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0007264 [small GTPase mediated signal transduction]
GO:0012507 [ER to Golgi transport vesicle membrane]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II]
GO:0031080 [nuclear pore outer ring]
GO:0032008 [positive regulation of TOR signaling]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0051028 [mRNA transport]
GO:0061024 [membrane organization]
GO:0061700 [GATOR2 complex]
GO:0070062 [extracellular exosome]
Show all
 308 aa
34 kDa 		No 0
SEC13-005
ENSP00000380306
ENST00000397117
A8MXL6 [Direct mapping]
Protein SEC13 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 284 aa
31.6 kDa 		No 0
SEC13-006
ENSP00000398623
ENST00000445064
C9JBJ5 [Direct mapping]
Protein SEC13 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 27 aa
3 kDa 		No 0
SEC13-007
ENSP00000400260
ENST00000428626
C9J0S2 [Direct mapping]
Protein SEC13 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 28 aa
3.1 kDa 		No 0
SEC13-012
ENSP00000401368
ENST00000431352
E7ERC8 [Direct mapping]
Protein SEC13 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 86 aa
9.6 kDa 		No 0
SEC13-019
ENSP00000404141
ENST00000432213
C9JIB6 [Direct mapping]
Protein SEC13 homolog
Show all
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 24 aa
2.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.