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LYZL4

GENERAL INFORMATION

Gene name

 LYZL4

Gene description

 Lysozyme-like 4

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Reliability score

 Approved based on 1 antibody.
HPA038806
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 LYZL4 (HGNC Symbol)

Synonyms

 LYC4, MGC26768

Description

 Lysozyme-like 4 (HGNC Symbol)

Entrez gene summary

 Lysozymes (see LYZ; MIM 153450), especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. LYZL4 is a member of a family of lysozyme-like genes (Zhang et al., 2005 [PubMed 16014814]).[supplied by OMIM, Apr 2009]

Chromosome

 3

Cytoband

 p22.1

Chromosome location (bp)

 42397078 - 42410600

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000157093 (version 83.38)

Entrez gene

 131375

UniProt

 Q96KX0 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q96KX0

Antibodypedia

 LYZL4 antibodies

PROTEIN BROWSER
LYZL4-001
LYZL4-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
LYZL4-001
ENSP00000287748
ENST00000287748
Q96KX0 [Direct mapping]
Lysozyme-like protein 4
A0A080YUZ5 [Target identity:100%; Query identity:100%]
Lysozyme A; Lysozyme-like 4
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003796 [lysozyme activity]
GO:0005576 [extracellular region]
GO:0005634 [nucleus]
GO:0008152 [metabolic process]
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 146 aa
16.4 kDa 		Yes 0
LYZL4-002
ENSP00000387897
ENST00000441172
Q96KX0 [Direct mapping]
Lysozyme-like protein 4
A0A080YUZ5 [Target identity:100%; Query identity:100%]
Lysozyme A; Lysozyme-like 4
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0003796 [lysozyme activity]
GO:0005576 [extracellular region]
GO:0005634 [nucleus]
GO:0008152 [metabolic process]
Show all
 146 aa
16.4 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.