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RBPMS

GENERAL INFORMATION

Gene name

 RBPMS

Gene description

 RNA binding protein with multiple splicing

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 9
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear and cytoplasmic expression in most tissues, highly abundant in smooth muscle.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA056999
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Seminal vesicle

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RBPMS (HGNC Symbol)

Synonyms

 HERMES

Description

 RNA binding protein with multiple splicing (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Chromosome

 8

Cytoband

 p12

Chromosome location (bp)

 30384479 - 30572261

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000157110 (version 83.38)

Entrez gene

 11030

UniProt

 Q93062 (UniProt - Evidence at protein level)

neXtProt

 NX_Q93062

Antibodypedia

 RBPMS antibodies

PROTEIN BROWSER
RBPMS-001
RBPMS-002
RBPMS-003
RBPMS-004
RBPMS-006
RBPMS-007
RBPMS-015
RBPMS-016
RBPMS-017

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RBPMS-001
ENSP00000380486
ENST00000397323
Q93062 [Direct mapping]
RNA-binding protein with multiple splicing
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0003676 [nucleic acid binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006396 [RNA processing]
GO:0008143 [poly(A) binding]
GO:0010862 [positive regulation of pathway-restricted SMAD protein phosphorylation]
GO:0017069 [snRNA binding]
GO:0044822 [poly(A) RNA binding]
GO:0060391 [positive regulation of SMAD protein import into nucleus]
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 196 aa
21.8 kDa 		No 0
RBPMS-002
ENSP00000318102
ENST00000320203
Q93062 [Direct mapping]
RNA-binding protein with multiple splicing
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0003676 [nucleic acid binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006396 [RNA processing]
GO:0008143 [poly(A) binding]
GO:0010862 [positive regulation of pathway-restricted SMAD protein phosphorylation]
GO:0017069 [snRNA binding]
GO:0044822 [poly(A) RNA binding]
GO:0060391 [positive regulation of SMAD protein import into nucleus]
Show all
 196 aa
21.8 kDa 		No 0
RBPMS-003
ENSP00000340176
ENST00000339877
Q93062 [Direct mapping]
RNA-binding protein with multiple splicing
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0003676 [nucleic acid binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006396 [RNA processing]
GO:0008143 [poly(A) binding]
GO:0010862 [positive regulation of pathway-restricted SMAD protein phosphorylation]
GO:0017069 [snRNA binding]
GO:0044822 [poly(A) RNA binding]
GO:0060391 [positive regulation of SMAD protein import into nucleus]
Show all
 219 aa
24.3 kDa 		No 0
RBPMS-004
ENSP00000287771
ENST00000287771
Q93062 [Direct mapping]
RNA-binding protein with multiple splicing
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0003676 [nucleic acid binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006396 [RNA processing]
GO:0008143 [poly(A) binding]
GO:0010862 [positive regulation of pathway-restricted SMAD protein phosphorylation]
GO:0017069 [snRNA binding]
GO:0044822 [poly(A) RNA binding]
GO:0060391 [positive regulation of SMAD protein import into nucleus]
Show all
 204 aa
22.4 kDa 		No 0
RBPMS-006
ENSP00000430638
ENST00000520191
E5RJ31 [Direct mapping]
RNA-binding protein with multiple-splicing
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
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 120 aa
13.4 kDa 		No 0
RBPMS-007
ENSP00000428675
ENST00000517860
B4E3T4 [Direct mapping]
HCG2043421, isoform CRA_c; RNA-binding protein with multiple-splicing; cDNA FLJ61582, highly similar to RNA-binding protein with multiple splicing
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0003676 [nucleic acid binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0017069 [snRNA binding]
Show all
 224 aa
25 kDa 		No 0
RBPMS-015
ENSP00000427896
ENST00000520161
E5RFP4 [Direct mapping]
RNA-binding protein with multiple-splicing
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 115 aa
12.7 kDa 		No 0
RBPMS-016
ENSP00000429086
ENST00000523115
E5RJD7 [Direct mapping]
RNA-binding protein with multiple-splicing
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 49 aa
5.4 kDa 		No 0
RBPMS-017
ENSP00000430342
ENST00000519647
E5RFP4 [Direct mapping]
RNA-binding protein with multiple-splicing
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 115 aa
12.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.