Cell atlas - HYDIN - The Human Protein Atlas

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HYDIN

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Plasma membrane

Human cell
	Cytosol
	Plasma Membrane

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GENERAL INFORMATION
Gene name	HYDIN
Gene description	HYDIN, axonemal central pair apparatus protein
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the plasma membrane & cytosol.
RNA cell category	Cell line enhanced (SiHa, RPTEC TERT1)
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA074129
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SiHa, RPTEC TERT1) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the plasma membrane & cytosol.

Main location

Plasma membrane (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA074129	SH-SY5Y	No staining
	HPA074129	SiHa	Plasma membrane
	HPA074129	SiHa	Cytosol
	HPA074129	U-2 OS	No staining

GENE INFORMATION
Gene name	HYDIN (HGNC Symbol)
Synonyms	CILD5, DKFZp434D0513, KIAA1864, PPP1R31
Description	HYDIN, axonemal central pair apparatus protein (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that may be involved in cilia motility. Mutations in this gene cause of autosomal recessive primary ciliary dyskinesia-5, a disorder characterized by the accumulation of cerebrospinal fluid within the ventricles of the brain. A duplicate copy of this gene has been found in humans on chromosome 1. [provided by RefSeq, Jan 2013]
Chromosome	16
Cytoband	q22.2
Chromosome location (bp)	70807378 - 71230722
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000157423 (version 83.38)
Entrez gene	54768
UniProt	Q4G0P3 (UniProt - Evidence at protein level)
neXtProt	NX_Q4G0P3
Antibodypedia	HYDIN antibodies

PROTEIN BROWSER

HYDIN-001	HYDIN-002	HYDIN-003	HYDIN-004	HYDIN-005	HYDIN-008	HYDIN-014	HYDIN-015	HYDIN-019	HYDIN-022

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HYDIN-001 ENSP00000377197 ENST00000393567	Q4G0P3 [Direct mapping] Hydrocephalus-inducing protein homolog Show all	Predicted intracellular proteins Disease related genes Show all	GO:0002064 [epithelial cell development] GO:0003341 [cilium movement] GO:0007275 [multicellular organismal development] GO:0021591 [ventricular system development] GO:0060438 [trachea development] GO:1904158 [axonemal central apparatus assembly] GO:1990718 [axonemal central pair projection] Show all	5121 aa 575.9 kDa	No	0
HYDIN-002 ENSP00000314736 ENST00000321489	Q4G0P3 [Direct mapping] Hydrocephalus-inducing protein homolog Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Show all		1017 aa 114.2 kDa	No	0
HYDIN-003 ENSP00000444970 ENST00000538248	Q4G0P3 [Direct mapping] Hydrocephalus-inducing protein homolog Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Show all		950 aa 106.3 kDa	No	0
HYDIN-004 ENSP00000437341 ENST00000541601	Q4G0P3 [Direct mapping] Hydrocephalus-inducing protein homolog Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Show all		940 aa 105.3 kDa	No	0
HYDIN-005 ENSP00000288168 ENST00000288168	F8WD03 [Direct mapping] Hydrocephalus-inducing protein homolog Show all	Predicted intracellular proteins Show all		725 aa 81.6 kDa	No	0
HYDIN-008 ENSP00000437598 ENST00000538382	H0YF91 [Direct mapping] Hydrocephalus-inducing protein homolog Show all	Predicted intracellular proteins Show all		204 aa 23.5 kDa	No	0
HYDIN-014 ENSP00000440202 ENST00000545267	F5GXK3 [Direct mapping] Hydrocephalus-inducing protein homolog Show all	Predicted intracellular proteins Show all		36 aa 4 kDa	No	0
HYDIN-015 ENSP00000443525 ENST00000539973	F5H8I6 [Direct mapping] Hydrocephalus-inducing protein homolog Show all	Predicted intracellular proteins Show all		39 aa 4.3 kDa	No	0
HYDIN-019 ENSP00000446122 ENST00000542890	H0YH52 [Direct mapping] Hydrocephalus-inducing protein homolog Show all	Predicted intracellular proteins Show all		127 aa 14.1 kDa	No	0
HYDIN-022 ENSP00000479502 ENST00000546297	A0A087WVK9 [Direct mapping] Hydrocephalus-inducing protein homolog Show all	Predicted intracellular proteins Show all		82 aa 9.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.