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DRC1

GENERAL INFORMATION

Gene name

 DRC1

Gene description

 Dynein regulatory complex subunit 1

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (fallopian tube, testis)
GTEx:Tissue enhanced (testis)
FANTOM5:Tissue enhanced (testis, epididymis)

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (fallopian tube, testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis, epididymis)

GENE INFORMATION

Gene name

 DRC1 (HGNC Symbol)

Synonyms

 C2orf39, CCDC164, CILD21, FLJ32660, MGC16372

Description

 Dynein regulatory complex subunit 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a central component of the nexin-dynein complex (N-DRC), which regulates the assembly of ciliary dynein. Mutations in this gene can cause ciliary dyskinesia. [provided by RefSeq, Aug 2015]

Chromosome

 2

Cytoband

 p23.3

Chromosome location (bp)

 26401916 - 26456711

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000157856 (version 83.38)

Entrez gene

 92749

UniProt

 Q96MC2 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q96MC2

Antibodypedia

 DRC1 antibodies

PROTEIN BROWSER
DRC1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DRC1-001
ENSP00000288710
ENST00000288710
Q96MC2 [Direct mapping]
Dynein regulatory complex protein 1
Show all
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Show all
GO:0005856 [cytoskeleton]
GO:0005930 [axoneme]
GO:0007368 [determination of left/right symmetry]
GO:0007507 [heart development]
GO:0060285 [cilium-dependent cell motility]
GO:0070286 [axonemal dynein complex assembly]
GO:0071973 [bacterial-type flagellum-dependent cell motility]
Show all
 740 aa
87.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.