Expression of RAB28 in cancer - Summary

CANCER ATLAS

Gene description

RAB28, member RAS oncogene family

Protein class

Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA044575

GENE INFORMATION
Gene name	RAB28
Synonyms
Description	RAB28, member RAS oncogene family (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 9 and X. [provided by RefSeq, Apr 2009]
Chromosome	4
Cytoband	p15.33
Chromosome location (bp)	13361354 - 13484365
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000157869 (version 83.38)
Entrez gene	9364
UniProt	P51157 (UniProt - Evidence at protein level)
neXtProt	NX_P51157
Antibodypedia	RAB28 antibodies

PROTEIN BROWSER

RAB28-001	RAB28-002	RAB28-005	RAB28-006	RAB28-008	RAB28-201	RAB28-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RAB28-001 ENSP00000328551 ENST00000330852	P51157 [Direct mapping] Ras-related protein Rab-28 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0019003 [GDP binding] GO:0035253 [ciliary rootlet] GO:0036064 [ciliary basal body] GO:1901998 [toxin transport] Show all	221 aa 24.8 kDa	No	0
RAB28-002 ENSP00000288723 ENST00000288723	P51157 [Direct mapping] Ras-related protein Rab-28 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0019003 [GDP binding] GO:0035253 [ciliary rootlet] GO:0036064 [ciliary basal body] Show all	220 aa 24.9 kDa	No	0
RAB28-005 ENSP00000424091 ENST00000510528	H0Y9G4 [Direct mapping] Ras-related protein Rab-28 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0007264 [small GTPase mediated signal transduction] Show all	51 aa 5.8 kDa	No	0
RAB28-006 ENSP00000424899 ENST00000511649	H0Y9S6 [Direct mapping] Ras-related protein Rab-28 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] Show all	143 aa 16.3 kDa	No	0
RAB28-008 ENSP00000422816 ENST00000504644	H0Y927 [Direct mapping] Ras-related protein Rab-28 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		74 aa 8.3 kDa	No	0
RAB28-201 ENSP00000340079 ENST00000338176	P51157 [Direct mapping] Ras-related protein Rab-28 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0019003 [GDP binding] GO:0035253 [ciliary rootlet] GO:0036064 [ciliary basal body] Show all	204 aa 23 kDa	No	0
RAB28-202 ENSP00000485808 ENST00000630951	Q8WVF3 [Direct mapping] RAB28 protein; Ras-related protein Rab-28 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0007264 [small GTPase mediated signal transduction] Show all	95 aa 10.6 kDa	No	0