Tissue expression of SLC30A2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	SLC30A2
Gene description	Solute carrier family 30 (zinc transporter), member 2
Protein class	Disease related genes Potential drug targets Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (thyroid gland, kidney)
GTEx:	Tissue enhanced (pancreas, kidney)
FANTOM5:	Tissue enhanced (pancreas, placenta)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland, kidney)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (pancreas, kidney)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (pancreas, placenta)

GENE INFORMATION
Gene name	SLC30A2 (HGNC Symbol)
Synonyms	ZNT2
Description	Solute carrier family 30 (zinc transporter), member 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a zinc transporter that acts as a homodimer. The encoded protein plays a role in secreting zinc into breast milk. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Chromosome	1
Cytoband	p36.11
Chromosome location (bp)	26037252 - 26046133
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000158014 (version 83.38)
Entrez gene	7780
UniProt	Q9BRI3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BRI3
Antibodypedia	SLC30A2 antibodies

PROTEIN BROWSER

SLC30A2-001	SLC30A2-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC30A2-001 ENSP00000363396 ENST00000374278	Q9BRI3 [Direct mapping] Zinc transporter 2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0005385 [zinc ion transmembrane transporter activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005765 [lysosomal membrane] GO:0005770 [late endosome] GO:0005886 [plasma membrane] GO:0006812 [cation transport] GO:0008324 [cation transmembrane transporter activity] GO:0010043 [response to zinc ion] GO:0016021 [integral component of membrane] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0055085 [transmembrane transport] GO:0061090 [positive regulation of sequestering of zinc ion] GO:0071577 [zinc II ion transmembrane transport] Show all	323 aa 35.2 kDa	No	4
SLC30A2-004 ENSP00000363394 ENST00000374276	Q9BRI3 [Direct mapping] Zinc transporter 2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0005385 [zinc ion transmembrane transporter activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005765 [lysosomal membrane] GO:0005770 [late endosome] GO:0005886 [plasma membrane] GO:0006812 [cation transport] GO:0006829 [zinc II ion transport] GO:0008324 [cation transmembrane transporter activity] GO:0010043 [response to zinc ion] GO:0016021 [integral component of membrane] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0055085 [transmembrane transport] GO:0061090 [positive regulation of sequestering of zinc ion] GO:0071577 [zinc II ion transmembrane transport] Show all	372 aa 40.6 kDa	No	6