Tissue expression of CPA5 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CPA5
Gene description	Carboxypeptidase A5
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	CPA5
Synonyms
Description	Carboxypeptidase A5 (HGNC Symbol)
Entrez gene summary	Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002 [PubMed 11836249]).[supplied by OMIM, Mar 2008]
Chromosome	7
Cytoband	q32.2
Chromosome location (bp)	130344816 - 130368730
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000158525 (version 83.38)
Entrez gene	93979
UniProt	Q8WXQ8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8WXQ8
Antibodypedia	CPA5 antibodies

PROTEIN BROWSER

CPA5-001	CPA5-003	CPA5-005	CPA5-006	CPA5-007	CPA5-008	CPA5-010	CPA5-011	CPA5-012	CPA5-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CPA5-001 ENSP00000420237 ENST00000485477	Q8WXQ8 [Direct mapping] Carboxypeptidase A5 A4D1M2 [Target identity:100%; Query identity:100%] Carboxypeptidase A5; Carboxypeptidase A5, isoform CRA_a Show all	Enzymes Peptidases Metallopeptidases MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004180 [carboxypeptidase activity] GO:0004181 [metallocarboxypeptidase activity] GO:0005615 [extracellular space] GO:0006508 [proteolysis] GO:0008233 [peptidase activity] GO:0008270 [zinc ion binding] Show all	436 aa 49 kDa	No	0
CPA5-003 ENSP00000376907 ENST00000393213	Q8WXQ8 [Direct mapping] Carboxypeptidase A5 A4D1M2 [Target identity:100%; Query identity:100%] Carboxypeptidase A5; Carboxypeptidase A5, isoform CRA_a Show all	Enzymes Peptidases Metallopeptidases MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004180 [carboxypeptidase activity] GO:0004181 [metallocarboxypeptidase activity] GO:0005615 [extracellular space] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	436 aa 49 kDa	No	0
CPA5-005 ENSP00000417314 ENST00000474905	Q8WXQ8 [Direct mapping] Carboxypeptidase A5 A4D1M2 [Target identity:100%; Query identity:100%] Carboxypeptidase A5; Carboxypeptidase A5, isoform CRA_a Show all	Enzymes Peptidases Metallopeptidases MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004180 [carboxypeptidase activity] GO:0004181 [metallocarboxypeptidase activity] GO:0005615 [extracellular space] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	436 aa 49 kDa	No	0
CPA5-006 ENSP00000419025 ENST00000466363	Q8WXQ8 [Direct mapping] Carboxypeptidase A5 A4D1M2 [Target identity:100%; Query identity:100%] Carboxypeptidase A5; Carboxypeptidase A5, isoform CRA_a Show all	Enzymes Peptidases Metallopeptidases MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004180 [carboxypeptidase activity] GO:0004181 [metallocarboxypeptidase activity] GO:0005615 [extracellular space] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	436 aa 49 kDa	No	0
CPA5-007 ENSP00000393045 ENST00000431780	Q8WXQ8 [Direct mapping] Carboxypeptidase A5 Show all	Enzymes Peptidases Metallopeptidases MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004180 [carboxypeptidase activity] GO:0004181 [metallocarboxypeptidase activity] GO:0005615 [extracellular space] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	403 aa 44.9 kDa	No	0
CPA5-008 ENSP00000418183 ENST00000461828	Q8WXQ8 [Direct mapping] Carboxypeptidase A5 A4D1M2 [Target identity:100%; Query identity:100%] Carboxypeptidase A5; Carboxypeptidase A5, isoform CRA_a Show all	Enzymes Peptidases Metallopeptidases MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004180 [carboxypeptidase activity] GO:0004181 [metallocarboxypeptidase activity] GO:0005615 [extracellular space] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	436 aa 49 kDa	No	0
CPA5-010 ENSP00000420060 ENST00000463587	C9JRV5 [Direct mapping] Carboxypeptidase A5 Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004180 [carboxypeptidase activity] GO:0006508 [proteolysis] Show all	123 aa 13.6 kDa	No	0
CPA5-011 ENSP00000419013 ENST00000497503		Predicted intracellular proteins Show all		8 aa 0.7 kDa	No	0
CPA5-012 ENSP00000419778 ENST00000494311	C9JZE9 [Direct mapping] Carboxypeptidase A5 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		32 aa 3.3 kDa	No	0
CPA5-013 ENSP00000417886 ENST00000479492	H7C4Q6 [Direct mapping] Carboxypeptidase A5 Show all	Predicted intracellular proteins Show all	GO:0004181 [metallocarboxypeptidase activity] GO:0006508 [proteolysis] GO:0008270 [zinc ion binding] Show all	85 aa 9.5 kDa	No	0