Expression of TAGLN2 in cancer - Summary

CANCER ATLAS

Gene description

Transgelin 2

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA001925

GENE INFORMATION
Gene name	TAGLN2 (HGNC Symbol)
Synonyms	HA1756, KIAA0120
Description	Transgelin 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
Chromosome	1
Cytoband	q23.2
Chromosome location (bp)	159918107 - 159925732
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000158710 (version 83.38)
Entrez gene	8407
UniProt	P37802 (UniProt - Evidence at protein level)
neXtProt	NX_P37802
Antibodypedia	TAGLN2 antibodies

PROTEIN BROWSER

TAGLN2-001	TAGLN2-002	TAGLN2-003	TAGLN2-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TAGLN2-001 ENSP00000357077 ENST00000368097	P37802 [Direct mapping] Transgelin-2 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0030855 [epithelial cell differentiation] GO:0031982 [vesicle] GO:0070062 [extracellular exosome] Show all	199 aa 22.4 kDa	No	0
TAGLN2-002 ENSP00000357076 ENST00000368096	P37802 [Direct mapping] Transgelin-2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0030855 [epithelial cell differentiation] GO:0031982 [vesicle] GO:0070062 [extracellular exosome] Show all	220 aa 24.5 kDa	Yes	0
TAGLN2-003 ENSP00000357075 ENST00000320307	P37802 [Direct mapping] Transgelin-2 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0030855 [epithelial cell differentiation] GO:0031982 [vesicle] GO:0070062 [extracellular exosome] Show all	199 aa 22.4 kDa	No	0
TAGLN2-004 ENSP00000412429 ENST00000397334	X6RJP6 [Direct mapping] Transgelin-2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	187 aa 21.1 kDa	No	0