Cell atlas - ZNF276 - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ZNF276
Gene description	Zinc finger protein 276
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleus & cytosol. In addition localized to the nucleoli & plasma membrane.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved), Cytosol (approved)
Additional location	In addition localized to the Nucleoli (approved), Plasma membrane (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA021309
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleus & cytosol. In addition localized to the nucleoli & plasma membrane.

Main location

Nucleus (approved), Cytosol (approved)

Additional location

Nucleoli (approved), Plasma membrane (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA021309	A-431	Nucleus
		Nucleoli
		Plasma membrane
		Cytosol
HPA021309	U-2 OS	Nucleus
		Nucleoli
		Cytosol
HPA021309	U-251 MG	Nucleoplasm
HPA021309	U-251 MG	Cytosol

GENE INFORMATION
Gene name	ZNF276 (HGNC Symbol)
Synonyms	CENP-Z, CENPZ, MGC45417, ZADT, ZFP276, ZNF477
Description	Zinc finger protein 276 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q24.3
Chromosome location (bp)	89720400 - 89740903
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000158805 (version 83.38)
Entrez gene	92822
UniProt	Q8N554 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N554
Antibodypedia	ZNF276 antibodies

PROTEIN BROWSER

ZNF276-001	ZNF276-002	ZNF276-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF276-001 ENSP00000289816 ENST00000289816	Q8N554 [Direct mapping] Zinc finger protein 276 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	539 aa 59.8 kDa	No	0
ZNF276-002 ENSP00000457210 ENST00000568064	H3BTK0 [Direct mapping] Zinc finger protein 276 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005634 [nucleus] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	433 aa 48.3 kDa	No	0
ZNF276-004 ENSP00000415836 ENST00000443381	Q8N554 [Direct mapping] Zinc finger protein 276 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	614 aa 67.2 kDa	No	0