Expression of C21orf59 in cancer - Summary

CANCER ATLAS

Gene description

Chromosome 21 open reading frame 59

Protein class

Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA018453	HPA019055	HPA028849	CAB034170

GENE INFORMATION
Gene name	C21orf59 (HGNC Symbol)
Synonyms	C21orf48, CILD26, FBB18, FLJ20467
Description	Chromosome 21 open reading frame 59 (HGNC Symbol)
Entrez gene summary	This gene a protein plays a critical role in dynein arm assembly and motile cilia function. Mutations in this gene result in primary ciliary dyskinesia. [provided by RefSeq, Nov 2013]
Chromosome	21
Cytoband	q22.11
Chromosome location (bp)	32592079 - 32612866
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159079 (version 83.38)
Entrez gene	56683
UniProt	P57076 (UniProt - Evidence at protein level)
neXtProt	NX_P57076
Antibodypedia	C21orf59 antibodies

PROTEIN BROWSER

C21orf59-001	C21orf59-002	C21orf59-004	C21orf59-005	C21orf59-006	C21orf59-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C21orf59-001 ENSP00000290155 ENST00000290155	P57076 [Direct mapping] UPF0769 protein C21orf59 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005829 [cytosol] GO:0048858 [cell projection morphogenesis] Show all	290 aa 33.2 kDa	No	0
C21orf59-002 ENSP00000371989 ENST00000382549	D3DSE6 [Direct mapping] Chromosome 21 open reading frame 59, isoform CRA_b; UPF0769 protein C21orf59 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		245 aa 27.6 kDa	No	0
C21orf59-004 ENSP00000407362 ENST00000425336	H7C2R6 [Direct mapping] UPF0769 protein C21orf59 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		117 aa 13.3 kDa	No	0
C21orf59-005 ENSP00000411306 ENST00000431599	H7C3D9 [Direct mapping] UPF0769 protein C21orf59 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		79 aa 8.5 kDa	No	0
C21orf59-006 ENSP00000411467 ENST00000440966	C9J818 [Direct mapping] UPF0769 protein C21orf59 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		258 aa 29.4 kDa	No	0
C21orf59-007 ENSP00000393104 ENST00000458138	C9JX57 [Direct mapping] UPF0769 protein C21orf59 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		184 aa 20.7 kDa	No	0