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MORC3

GENERAL INFORMATION

Gene name

 MORC3

Gene description

 MORC family CW-type zinc finger 3

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear and cytoplasmic expression in all tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA018406
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 MORC3 (HGNC Symbol)

Synonyms

 KIAA0136, NXP2, ZCW5, ZCWCC3

Description

 MORC family CW-type zinc finger 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that localizes to the nuclear matrix. The protein also has RNA binding activity, and has a predicted coiled-coil domain. [provided by RefSeq, Jul 2008]

Chromosome

 21

Cytoband

 q22.12

Chromosome location (bp)

 36320189 - 36386148

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000159256 (version 83.38)

Entrez gene

 23515

UniProt

 Q14149 (UniProt - Evidence at protein level)

neXtProt

 NX_Q14149

Antibodypedia

 MORC3 antibodies

PROTEIN BROWSER
MORC3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MORC3-001
ENSP00000383333
ENST00000400485
Q14149 [Direct mapping]
MORC family CW-type zinc finger protein 3
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005654 [nucleoplasm]
GO:0006468 [protein phosphorylation]
GO:0007569 [cell aging]
GO:0008270 [zinc ion binding]
GO:0016605 [PML body]
GO:0018105 [peptidyl-serine phosphorylation]
GO:0045111 [intermediate filament cytoskeleton]
GO:0048147 [negative regulation of fibroblast proliferation]
GO:0050821 [protein stabilization]
GO:0051457 [maintenance of protein location in nucleus]
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 939 aa
107.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.