Fields »
ABOUT
HELP
BLOG
ARHGAP27

CANCER ATLAS

Gene description

 Rho GTPase activating protein 27

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA023919

GENE INFORMATION

Gene name

 ARHGAP27 (HGNC Symbol)

Synonyms

 CAMGAP1, FLJ43547, SH3D20, SH3P20

Description

 Rho GTPase activating protein 27 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013]

Chromosome

 17

Cytoband

 q21.31

Chromosome location (bp)

 45393902 - 45434421

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000159314 (version 83.38)

Entrez gene

 201176

UniProt

 Q6ZUM4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6ZUM4

Antibodypedia

 ARHGAP27 antibodies

PROTEIN BROWSER
ARHGAP27-001
ARHGAP27-003
ARHGAP27-004
ARHGAP27-006
ARHGAP27-009
ARHGAP27-011
ARHGAP27-201
ARHGAP27-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARHGAP27-001
ENSP00000366121
ENST00000376922
Q6ZUM4 [Direct mapping]
Rho GTPase-activating protein 27
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0006898 [receptor-mediated endocytosis]
GO:0007165 [signal transduction]
GO:0016020 [membrane]
GO:0017124 [SH3 domain binding]
GO:0043547 [positive regulation of GTPase activity]
Show all
 548 aa
61.7 kDa 		No 0
ARHGAP27-003
ENSP00000432762
ENST00000532038
E9PNT2 [Direct mapping]
Rho GTPase-activating protein 27
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0007165 [signal transduction]
Show all
 667 aa
75 kDa 		No 0
ARHGAP27-004
ENSP00000437100
ENST00000528677
E9PNX6 [Direct mapping]
Rho GTPase-activating protein 27
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 214 aa
23.4 kDa 		No 0
ARHGAP27-006
ENSP00000431591
ENST00000528384
A0A0C4DGE6 [Direct mapping]
Rho GTPase-activating protein 27
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0007165 [signal transduction]
GO:0043547 [positive regulation of GTPase activity]
Show all
 521 aa
58.4 kDa 		No 0
ARHGAP27-009
ENSP00000433942
ENST00000532891
E9PIR1 [Direct mapping]
Rho GTPase-activating protein 27
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0007165 [signal transduction]
Show all
 867 aa
96.1 kDa 		No 0
ARHGAP27-011
ENSP00000436137
ENST00000528273
Q6ZUM4 [Direct mapping]
Rho GTPase-activating protein 27
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0006898 [receptor-mediated endocytosis]
GO:0007165 [signal transduction]
GO:0016020 [membrane]
GO:0017124 [SH3 domain binding]
GO:0043547 [positive regulation of GTPase activity]
Show all
 263 aa
28.2 kDa 		No 0
ARHGAP27-201
ENSP00000290470
ENST00000290470
Q6ZUM4 [Direct mapping]
Rho GTPase-activating protein 27
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0006898 [receptor-mediated endocytosis]
GO:0007165 [signal transduction]
GO:0016020 [membrane]
GO:0017124 [SH3 domain binding]
GO:0043547 [positive regulation of GTPase activity]
Show all
 263 aa
28.2 kDa 		No 0
ARHGAP27-202
ENSP00000403323
ENST00000428638
Q6ZUM4 [Direct mapping]
Rho GTPase-activating protein 27
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0006898 [receptor-mediated endocytosis]
GO:0007165 [signal transduction]
GO:0016020 [membrane]
GO:0017124 [SH3 domain binding]
GO:0043547 [positive regulation of GTPase activity]
Show all
 889 aa
98.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.