Cell atlas - PADI4 - The Human Protein Atlas

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PADI4

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	PADI4
Gene description	Peptidyl arginine deiminase, type IV
Protein class	Disease related genes Enzymes Plasma proteins Potential drug targets Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (HEL, RPMI-8226)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HEL, RPMI-8226) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	PADI4 (HGNC Symbol)
Synonyms	PAD, PADI5, PDI4, PDI5
Description	Peptidyl arginine deiminase, type IV (HGNC Symbol)
Entrez gene summary	This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p36.13
Chromosome location (bp)	17308195 - 17364004
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159339 (version 83.38)
Entrez gene	23569
UniProt	Q9UM07 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UM07
Antibodypedia	PADI4 antibodies

PROTEIN BROWSER

PADI4-001	PADI4-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PADI4-001 ENSP00000364597 ENST00000375448	Q9UM07 [Direct mapping] Protein-arginine deiminase type-4 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004668 [protein-arginine deiminase activity] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006334 [nucleosome assembly] GO:0006338 [chromatin remodeling] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006464 [cellular protein modification process] GO:0016568 [chromatin modification] GO:0016990 [arginine deiminase activity] GO:0018101 [protein citrullination] GO:0019827 [stem cell population maintenance] GO:0036413 [histone H3-R26 citrullination] GO:0036414 [histone citrullination] GO:0045087 [innate immune response] Show all	663 aa 74.1 kDa	No	0
PADI4-002 ENSP00000364602 ENST00000375453	B1AQ67 [Direct mapping] Protein-arginine deiminase type-4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004668 [protein-arginine deiminase activity] GO:0005509 [calcium ion binding] GO:0005737 [cytoplasm] GO:0018101 [protein citrullination] Show all	127 aa 13.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.