Tissue expression of ADIPOR1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ADIPOR1
Gene description	Adiponectin receptor 1
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ADIPOR1 (HGNC Symbol)
Synonyms	ACDCR1, PAQR1
Description	Adiponectin receptor 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]
Chromosome	1
Cytoband	q32.1
Chromosome location (bp)	202940823 - 202958572
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159346 (version 83.38)
Entrez gene	51094
UniProt	Q96A54 (UniProt - Evidence at protein level)
neXtProt	NX_Q96A54
Antibodypedia	ADIPOR1 antibodies

PROTEIN BROWSER

ADIPOR1-001	ADIPOR1-002	ADIPOR1-003	ADIPOR1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADIPOR1-001 ENSP00000341785 ENST00000340990	Q96A54 [Direct mapping] Adiponectin receptor protein 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0009755 [hormone-mediated signaling pathway] GO:0010906 [regulation of glucose metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019216 [regulation of lipid metabolic process] GO:0019395 [fatty acid oxidation] GO:0019901 [protein kinase binding] GO:0030308 [negative regulation of cell growth] GO:0031226 [intrinsic component of plasma membrane] GO:0033210 [leptin-mediated signaling pathway] GO:0033211 [adiponectin-activated signaling pathway] GO:0042593 [glucose homeostasis] GO:0042802 [identical protein binding] GO:0046427 [positive regulation of JAK-STAT cascade] GO:0046628 [positive regulation of insulin receptor signaling pathway] GO:0046872 [metal ion binding] GO:0046982 [protein heterodimerization activity] GO:0055100 [adiponectin binding] GO:0097003 [adipokinetic hormone receptor activity] Show all	375 aa 42.6 kDa	No	7
ADIPOR1-002 ENSP00000402178 ENST00000417068	C9JNM5 [Direct mapping] Adiponectin receptor protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0016021 [integral component of membrane] GO:0033211 [adiponectin-activated signaling pathway] Show all	266 aa 30.6 kDa	No	4
ADIPOR1-003 ENSP00000392946 ENST00000426229	C9J0W7 [Direct mapping] Adiponectin receptor protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0016021 [integral component of membrane] GO:0033211 [adiponectin-activated signaling pathway] Show all	205 aa 23.6 kDa	No	2
ADIPOR1-201 ENSP00000356223 ENST00000367254	F8W782 [Direct mapping] Adiponectin receptor protein 1 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0016021 [integral component of membrane] GO:0033211 [adiponectin-activated signaling pathway] Show all	171 aa 19.3 kDa	No	0