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CELF3

CANCER ATLAS

Gene description

 CUGBP, Elav-like family member 3

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA006292

GENE INFORMATION

Gene name

 CELF3 (HGNC Symbol)

Synonyms

 BRUNOL1, CAGH4, ERDA4, MGC57297, TNRC4

Description

 CUGBP, Elav-like family member 3 (HGNC Symbol)

Entrez gene summary

 Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]

Chromosome

 1

Cytoband

 q21.3

Chromosome location (bp)

 151702404 - 151716814

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000159409 (version 83.38)

Entrez gene

 11189

UniProt

 Q5SZQ8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5SZQ8

Antibodypedia

 CELF3 antibodies

PROTEIN BROWSER
CELF3-001
CELF3-002
CELF3-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CELF3-001
ENSP00000290583
ENST00000290583
Q5SZQ8 [Direct mapping]
CUGBP Elav-like family member 3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000381 [regulation of alternative mRNA splicing, via spliceosome]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0003729 [mRNA binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007283 [spermatogenesis]
GO:0008380 [RNA splicing]
GO:0030317 [sperm motility]
GO:0048026 [positive regulation of mRNA splicing, via spliceosome]
Show all
 465 aa
50.5 kDa 		No 0
CELF3-002
ENSP00000290585
ENST00000290585
Q5SZQ8 [Direct mapping]
CUGBP Elav-like family member 3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000381 [regulation of alternative mRNA splicing, via spliceosome]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0003729 [mRNA binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0008380 [RNA splicing]
GO:0048026 [positive regulation of mRNA splicing, via spliceosome]
Show all
 415 aa
45.7 kDa 		No 0
CELF3-003
ENSP00000402503
ENST00000420342
H0Y623 [Direct mapping]
CUGBP Elav-like family member 3
Show all
Predicted intracellular proteins
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
Show all
 466 aa
50.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.