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LCE2B

GENERAL INFORMATION

Gene name

 LCE2B

Gene description

 Late cornified envelope 2B

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (skin)
GTEx:Tissue enriched (skin)

Protein evidence

 Evidence at transcript level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skin)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skin)

GENE INFORMATION

Gene name

 LCE2B (HGNC Symbol)

Synonyms

 LEP10, SPRL1B, XP5

Description

 Late cornified envelope 2B (HGNC Symbol)

Entrez gene summary

 This gene is one of the at least 20 genes expressed during epidermal differentiation and located on chromosomal band 1q21. This gene is involved in epidermal differentiation, and it is expressed at high levels in normal and psoriatic skin, but not in cultured keratinocytes or in any other tested cell types or tissues. [provided by RefSeq, Jul 2008]

Chromosome

 1

Cytoband

 q21.3

Chromosome location (bp)

 152686123 - 152687401

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000159455 (version 83.38)

Entrez gene

 26239

UniProt

 O14633 (UniProt - Evidence at transcript level)

neXtProt

 NX_O14633

Antibodypedia

 LCE2B antibodies

PROTEIN BROWSER
LCE2B-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
LCE2B-001
ENSP00000357769
ENST00000368780
O14633 [Direct mapping]
Late cornified envelope protein 2B
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Predicted intracellular proteins
Show all
GO:0001533 [cornified envelope]
GO:0003674 [molecular_function]
GO:0005198 [structural molecule activity]
GO:0005575 [cellular_component]
GO:0005737 [cytoplasm]
GO:0008544 [epidermis development]
GO:0018149 [peptide cross-linking]
GO:0030216 [keratinocyte differentiation]
GO:0031424 [keratinization]
Show all
 110 aa
11.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.