We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Q13363 [Direct mapping] C-terminal-binding protein 1 X5D8Y5 [Target identity:100%; Query identity:100%] C-terminal binding protein 1 isoform C
Show all
SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001106 [RNA polymerase II transcription corepressor activity] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006468 [protein phosphorylation] GO:0008022 [protein C-terminus binding] GO:0008134 [transcription factor binding] GO:0008152 [metabolic process] GO:0008285 [negative regulation of cell proliferation] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0017053 [transcriptional repressor complex] GO:0019079 [viral genome replication] GO:0019904 [protein domain specific binding] GO:0031065 [positive regulation of histone deacetylation] GO:0035067 [negative regulation of histone acetylation] GO:0042803 [protein homodimerization activity] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0050872 [white fat cell differentiation] GO:0051287 [NAD binding] GO:0051726 [regulation of cell cycle] GO:0055114 [oxidation-reduction process] GO:0070404 [NADH binding] GO:0070491 [repressing transcription factor binding] GO:0090241 [negative regulation of histone H4 acetylation] GO:1903758 [negative regulation of transcription from RNA polymerase II promoter by histone modification]
E9PGB1 [Direct mapping] C-terminal-binding protein 1
Show all
Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008152 [metabolic process] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0051287 [NAD binding] GO:0055114 [oxidation-reduction process]
Q13363 [Direct mapping] C-terminal-binding protein 1
Show all
SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001106 [RNA polymerase II transcription corepressor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006468 [protein phosphorylation] GO:0008022 [protein C-terminus binding] GO:0008134 [transcription factor binding] GO:0008152 [metabolic process] GO:0008285 [negative regulation of cell proliferation] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0017053 [transcriptional repressor complex] GO:0019079 [viral genome replication] GO:0019904 [protein domain specific binding] GO:0031065 [positive regulation of histone deacetylation] GO:0035067 [negative regulation of histone acetylation] GO:0042803 [protein homodimerization activity] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0050872 [white fat cell differentiation] GO:0051287 [NAD binding] GO:0051726 [regulation of cell cycle] GO:0055114 [oxidation-reduction process] GO:0070404 [NADH binding] GO:0070491 [repressing transcription factor binding] GO:0090241 [negative regulation of histone H4 acetylation] GO:1903758 [negative regulation of transcription from RNA polymerase II promoter by histone modification]
D6RAX2 [Direct mapping] C-terminal-binding protein 1
Show all
SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008152 [metabolic process] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0051287 [NAD binding] GO:0055114 [oxidation-reduction process]
E7ESU7 [Direct mapping] C-terminal-binding protein 1
Show all
Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008152 [metabolic process] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0051287 [NAD binding] GO:0055114 [oxidation-reduction process]
H0Y8W7 [Direct mapping] C-terminal-binding protein 1
Show all
Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008152 [metabolic process] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0051287 [NAD binding] GO:0055114 [oxidation-reduction process]
E7EPF8 [Direct mapping] C-terminal-binding protein 1
Show all
MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008152 [metabolic process] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0051287 [NAD binding] GO:0055114 [oxidation-reduction process]
