Expression of ZFYVE28 in cancer - Summary

CANCER ATLAS

Gene description

Zinc finger, FYVE domain containing 28

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA038175	HPA057587

GENE INFORMATION
Gene name	ZFYVE28 (HGNC Symbol)
Synonyms	KIAA1643
Description	Zinc finger, FYVE domain containing 28 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	p16.3
Chromosome location (bp)	2269582 - 2418663
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159733 (version 83.38)
Entrez gene	57732
UniProt	Q9HCC9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HCC9
Antibodypedia	ZFYVE28 antibodies

PROTEIN BROWSER

ZFYVE28-001	ZFYVE28-002	ZFYVE28-003	ZFYVE28-004	ZFYVE28-006	ZFYVE28-007	ZFYVE28-008	ZFYVE28-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZFYVE28-001 ENSP00000290974 ENST00000290974	Q9HCC9 [Direct mapping] Lateral signaling target protein 2 homolog Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0007175 [negative regulation of epidermal growth factor-activated receptor activity] GO:0031901 [early endosome membrane] GO:0032266 [phosphatidylinositol-3-phosphate binding] GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway] GO:0046872 [metal ion binding] Show all	887 aa 96.5 kDa	No	0
ZFYVE28-002 ENSP00000425706 ENST00000511071	Q9HCC9 [Direct mapping] Lateral signaling target protein 2 homolog Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0007175 [negative regulation of epidermal growth factor-activated receptor activity] GO:0031901 [early endosome membrane] GO:0032266 [phosphatidylinositol-3-phosphate binding] GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway] GO:0046872 [metal ion binding] Show all	857 aa 93 kDa	No	0
ZFYVE28-003 ENSP00000423694 ENST00000503000	Q9HCC9 [Direct mapping] Lateral signaling target protein 2 homolog Show all	Predicted intracellular proteins Plasma proteins Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0007175 [negative regulation of epidermal growth factor-activated receptor activity] GO:0031901 [early endosome membrane] GO:0032266 [phosphatidylinositol-3-phosphate binding] GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway] GO:0046872 [metal ion binding] Show all	287 aa 32.7 kDa	No	0
ZFYVE28-004 ENSP00000427654 ENST00000508471	Q49AA1 [Direct mapping] Lateral-signaling target protein 2 homolog; ZFYVE28 protein Show all	Predicted intracellular proteins Show all	GO:0046872 [metal ion binding] Show all	192 aa 21.4 kDa	No	0
ZFYVE28-006 ENSP00000426299 ENST00000515312	Q9HCC9 [Direct mapping] Lateral signaling target protein 2 homolog Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0007175 [negative regulation of epidermal growth factor-activated receptor activity] GO:0031901 [early endosome membrane] GO:0032266 [phosphatidylinositol-3-phosphate binding] GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway] GO:0046872 [metal ion binding] Show all	817 aa 88.1 kDa	No	0
ZFYVE28-007 ENSP00000425766 ENST00000515169	Q9HCC9 [Direct mapping] Lateral signaling target protein 2 homolog Show all	Predicted intracellular proteins Plasma proteins Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0007175 [negative regulation of epidermal growth factor-activated receptor activity] GO:0031901 [early endosome membrane] GO:0032266 [phosphatidylinositol-3-phosphate binding] GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway] GO:0046872 [metal ion binding] Show all	163 aa 18.9 kDa	No	0
ZFYVE28-008 ENSP00000422638 ENST00000509171	Q9HCC9 [Direct mapping] Lateral signaling target protein 2 homolog Show all	Predicted intracellular proteins Plasma proteins Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0007175 [negative regulation of epidermal growth factor-activated receptor activity] GO:0031901 [early endosome membrane] GO:0032266 [phosphatidylinositol-3-phosphate binding] GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway] GO:0046872 [metal ion binding] Show all	172 aa 20.2 kDa	No	0
ZFYVE28-009 ENSP00000427471 ENST00000508184	D6RID3 [Direct mapping] Lateral-signaling target protein 2 homolog Show all	Predicted intracellular proteins Show all		82 aa 9.3 kDa	No	0