Tissue expression of UBE2J2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	UBE2J2
Gene description	Ubiquitin-conjugating enzyme E2, J2
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	UBE2J2 (HGNC Symbol)
Synonyms	NCUBE2, Ubc6p
Description	Ubiquitin-conjugating enzyme E2, J2 (HGNC Symbol)
Entrez gene summary	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p36.33
Chromosome location (bp)	1253909 - 1273885
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000160087 (version 83.38)
Entrez gene	118424
UniProt	Q8N2K1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N2K1
Antibodypedia	UBE2J2 antibodies

PROTEIN BROWSER

UBE2J2-001	UBE2J2-010	UBE2J2-011	UBE2J2-013	UBE2J2-014	UBE2J2-015	UBE2J2-016	UBE2J2-017	UBE2J2-019	UBE2J2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UBE2J2-001 ENSP00000305826 ENST00000349431	Q8N2K1 [Direct mapping] Ubiquitin-conjugating enzyme E2 J2 A0A024R075 [Target identity:100%; Query identity:100%] Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast), isoform CRA_b Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000151 [ubiquitin ligase complex] GO:0000209 [protein polyubiquitination] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006986 [response to unfolded protein] GO:0016021 [integral component of membrane] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] GO:0061631 [ubiquitin conjugating enzyme activity] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	259 aa 28.9 kDa	No	1
UBE2J2-010 ENSP00000393301 ENST00000435198	B1AMF0 [Direct mapping] Ubiquitin-conjugating enzyme E2 J2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000209 [protein polyubiquitination] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] Show all	196 aa 22.3 kDa	No	0
UBE2J2-011 ENSP00000353653 ENST00000360466	Q8N2K1 [Direct mapping] Ubiquitin-conjugating enzyme E2 J2 A0A024R075 [Target identity:100%; Query identity:100%] Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast), isoform CRA_b Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000151 [ubiquitin ligase complex] GO:0000209 [protein polyubiquitination] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006986 [response to unfolded protein] GO:0016021 [integral component of membrane] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] GO:0061631 [ubiquitin conjugating enzyme activity] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	259 aa 28.9 kDa	No	1
UBE2J2-013 ENSP00000427244 ENST00000488418	D6REN4 [Direct mapping] Ubiquitin-conjugating enzyme E2 J2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000209 [protein polyubiquitination] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] Show all	43 aa 4.8 kDa	No	0
UBE2J2-014 ENSP00000401898 ENST00000422076	B1AMF1 [Direct mapping] Ubiquitin-conjugating enzyme E2 J2 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000209 [protein polyubiquitination] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] Show all	101 aa 11.9 kDa	No	0
UBE2J2-015 ENSP00000383719 ENST00000400930	Q8N2K1 [Direct mapping] Ubiquitin-conjugating enzyme E2 J2 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000151 [ubiquitin ligase complex] GO:0000209 [protein polyubiquitination] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006986 [response to unfolded protein] GO:0016021 [integral component of membrane] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] GO:0061631 [ubiquitin conjugating enzyme activity] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	275 aa 31 kDa	No	1
UBE2J2-016 ENSP00000383718 ENST00000400929	A6NGS0 [Direct mapping] Ubiquitin-conjugating enzyme E2 J2; Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast), isoform CRA_e Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000209 [protein polyubiquitination] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0016021 [integral component of membrane] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] Show all	207 aa 22.9 kDa	No	1
UBE2J2-017 ENSP00000424342 ENST00000502382	D6RB84 [Direct mapping] Ubiquitin-conjugating enzyme E2 J2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000209 [protein polyubiquitination] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] Show all	71 aa 8.3 kDa	No	0
UBE2J2-019 ENSP00000425419 ENST00000509720	D6RD90 [Direct mapping] Ubiquitin-conjugating enzyme E2 J2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000209 [protein polyubiquitination] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] Show all	60 aa 6.8 kDa	No	0
UBE2J2-201 ENSP00000344857 ENST00000347370	A6NGS0 [Direct mapping] Ubiquitin-conjugating enzyme E2 J2; Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast), isoform CRA_e Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000209 [protein polyubiquitination] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0016021 [integral component of membrane] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0031625 [ubiquitin protein ligase binding] GO:0061630 [ubiquitin protein ligase activity] Show all	207 aa 22.9 kDa	No	1