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NDUFV3

GENERAL INFORMATION

Gene name

 NDUFV3

Gene description

 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression with a granular pattern.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 4 antibodies.
HPA019791 , HPA020463 , HPA030427 , CAB034142
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 NDUFV3 (HGNC Symbol)

Synonyms

 CI-10k

Description

 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 21

Cytoband

 q22.3

Chromosome location (bp)

 42879644 - 42913304

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000160194 (version 83.38)

Entrez gene

 4731

UniProt

 P56181 (UniProt - Evidence at protein level)

neXtProt

 NX_P56181

Antibodypedia

 NDUFV3 antibodies

PROTEIN BROWSER
NDUFV3-002
NDUFV3-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NDUFV3-002
ENSP00000346196
ENST00000354250
P56181 [Direct mapping]
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0005747 [mitochondrial respiratory chain complex I]
GO:0006120 [mitochondrial electron transport, NADH to ubiquinone]
GO:0008137 [NADH dehydrogenase (ubiquinone) activity]
GO:0022904 [respiratory electron transport chain]
GO:0044237 [cellular metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0044822 [poly(A) RNA binding]
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 473 aa
51 kDa 		No 0
NDUFV3-003
ENSP00000342895
ENST00000340344
P56181 [Direct mapping]
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0005747 [mitochondrial respiratory chain complex I]
GO:0006120 [mitochondrial electron transport, NADH to ubiquinone]
GO:0008137 [NADH dehydrogenase (ubiquinone) activity]
GO:0022904 [respiratory electron transport chain]
GO:0044237 [cellular metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 108 aa
11.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.