Tissue expression of SYCE2 - Summary - The Human Protein Atlas

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SYCE2

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TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SYCE2
Gene description	Synaptonemal complex central element protein 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression spermatocytes.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA042080
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	SYCE2 (HGNC Symbol)
Synonyms	CESC1
Description	Synaptonemal complex central element protein 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is part of the synaptonemal complex formed between homologous chromosomes during meiotic prophase. The encoded protein associates with SYCP1 and SYCE1 and is found only where chromosome cores are synapsed. [provided by RefSeq, Dec 2012]
Chromosome	19
Cytoband	p13.13
Chromosome location (bp)	12898786 - 12919276
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000161860 (version 83.38)
Entrez gene	256126
UniProt	Q6PIF2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6PIF2
Antibodypedia	SYCE2 antibodies

PROTEIN BROWSER

SYCE2-001	SYCE2-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SYCE2-001 ENSP00000293695 ENST00000293695	Q6PIF2 [Direct mapping] Synaptonemal complex central element protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0000801 [central element] GO:0005515 [protein binding] GO:0007130 [synaptonemal complex assembly] GO:0051301 [cell division] Show all	218 aa 24.7 kDa	No	0
SYCE2-004 ENSP00000466359 ENST00000592819	K7EM50 [Direct mapping] Synaptonemal complex central element protein 2 Show all	Predicted intracellular proteins Show all		54 aa 5.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.