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CMPK1

CANCER ATLAS

Gene description

 Cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

Protein class

 Enzymes, Plasma proteins, Predicted secreted proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Pancreatic cancer

STAINING SUMMARY
HPA053730
HPA058604

GENE INFORMATION

Gene name

 CMPK1 (HGNC Symbol)

Synonyms

 CMPK, UMP-CMPK

Description

 Cytidine monophosphate (UMP-CMP) kinase 1, cytosolic (HGNC Symbol)

Entrez gene summary

 This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012]

Chromosome

 1

Cytoband

 p33

Chromosome location (bp)

 47333797 - 47378839

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000162368 (version 83.38)

Entrez gene

 51727

UniProt

 P30085 (UniProt - Evidence at protein level)

neXtProt

 NX_P30085

Antibodypedia

 CMPK1 antibodies

PROTEIN BROWSER
CMPK1-001
CMPK1-002
CMPK1-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CMPK1-001
ENSP00000360939
ENST00000371873
P30085 [Direct mapping]
UMP-CMP kinase
B2R6S5 [Target identity:100%; Query identity:100%]
UMP-CMP kinase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004127 [cytidylate kinase activity]
GO:0004550 [nucleoside diphosphate kinase activity]
GO:0004849 [uridine kinase activity]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006139 [nucleobase-containing compound metabolic process]
GO:0006165 [nucleoside diphosphate phosphorylation]
GO:0006207 ['de novo' pyrimidine nucleobase biosynthetic process]
GO:0006221 [pyrimidine nucleotide biosynthetic process]
GO:0006222 [UMP biosynthetic process]
GO:0009041 [uridylate kinase activity]
GO:0009142 [nucleoside triphosphate biosynthetic process]
GO:0009220 [pyrimidine ribonucleotide biosynthetic process]
GO:0015949 [nucleobase-containing small molecule interconversion]
GO:0019205 [nucleobase-containing compound kinase activity]
GO:0044281 [small molecule metabolic process]
GO:0055086 [nucleobase-containing small molecule metabolic process]
GO:0070062 [extracellular exosome]
Show all
 228 aa
25.9 kDa 		Yes 0
CMPK1-002
ENSP00000433782
ENST00000471289
E9PJD2 [Direct mapping]
UMP-CMP kinase
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 58 aa
6.2 kDa 		Yes 0
CMPK1-005
ENSP00000398192
ENST00000450808
P30085 [Direct mapping]
UMP-CMP kinase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004127 [cytidylate kinase activity]
GO:0004550 [nucleoside diphosphate kinase activity]
GO:0004849 [uridine kinase activity]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006139 [nucleobase-containing compound metabolic process]
GO:0006165 [nucleoside diphosphate phosphorylation]
GO:0006207 ['de novo' pyrimidine nucleobase biosynthetic process]
GO:0006222 [UMP biosynthetic process]
GO:0009041 [uridylate kinase activity]
GO:0009142 [nucleoside triphosphate biosynthetic process]
GO:0009220 [pyrimidine ribonucleotide biosynthetic process]
GO:0015949 [nucleobase-containing small molecule interconversion]
GO:0019205 [nucleobase-containing compound kinase activity]
GO:0044281 [small molecule metabolic process]
GO:0055086 [nucleobase-containing small molecule metabolic process]
GO:0070062 [extracellular exosome]
Show all
 179 aa
20.2 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.