Expression of MAGOH in cancer - Summary

CANCER ATLAS

Gene description

Mago homolog, exon junction complex core component

Protein class

Predicted intracellular proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA043036	HPA047754	CAB015425

GENE INFORMATION
Gene name	MAGOH (HGNC Symbol)
Synonyms	MAGOH1, MAGOHA
Description	Mago homolog, exon junction complex core component (HGNC Symbol)
Entrez gene summary	Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p32.3
Chromosome location (bp)	53226892 - 53238610
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162385 (version 83.38)
Entrez gene	4116
UniProt	P61326 (UniProt - Evidence at protein level)
neXtProt	NX_P61326
Antibodypedia	MAGOH antibodies

PROTEIN BROWSER

MAGOH-001	MAGOH-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MAGOH-001 ENSP00000360525 ENST00000371470	P61326 [Direct mapping] Protein mago nashi homolog Show all	Transporters Primary Active Transporters SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0000398 [mRNA splicing, via spliceosome] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005829 [cytosol] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006369 [termination of RNA polymerase II transcription] GO:0006406 [mRNA export from nucleus] GO:0006417 [regulation of translation] GO:0008380 [RNA splicing] GO:0010467 [gene expression] GO:0016607 [nuclear speck] GO:0031124 [mRNA 3'-end processing] GO:0035145 [exon-exon junction complex] GO:0044822 [poly(A) RNA binding] GO:0071013 [catalytic step 2 spliceosome] Show all	146 aa 17.2 kDa	No	0
MAGOH-002 ENSP00000360521 ENST00000371466	P61326 [Direct mapping] Protein mago nashi homolog Show all	Transporters Primary Active Transporters Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0000398 [mRNA splicing, via spliceosome] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005829 [cytosol] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006369 [termination of RNA polymerase II transcription] GO:0006406 [mRNA export from nucleus] GO:0006417 [regulation of translation] GO:0008380 [RNA splicing] GO:0010467 [gene expression] GO:0016607 [nuclear speck] GO:0031124 [mRNA 3'-end processing] GO:0035145 [exon-exon junction complex] GO:0044822 [poly(A) RNA binding] GO:0071013 [catalytic step 2 spliceosome] Show all	109 aa 12.8 kDa	No	0