Cell atlas - RBP7 - The Human Protein Atlas

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RBP7

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nuclear speckles

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	RBP7
Gene description	Retinol binding protein 7, cellular
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol & nuclear speckles.
RNA cell category	Cell line enhanced (T-47d, EFO-21)
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear speckles (uncertain), Cytosol (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA034749
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (T-47d, EFO-21) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol & nuclear speckles.

Main location

Nuclear speckles (uncertain), Cytosol (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA034749	PC-3	Nuclear speckles
	HPA034749	PC-3	Cytosol
	HPA034749	U-251 MG	Cytosol

GENE INFORMATION
Gene name	RBP7 (HGNC Symbol)
Synonyms	CRBPIV
Description	Retinol binding protein 7, cellular (HGNC Symbol)
Entrez gene summary	Due to its chemical instability and low solubility in aqueous solution, vitamin A requires cellular retinol-binding proteins (CRBPs), such as RBP7, for stability, internalization, intercellular transfer, homeostasis, and metabolism.[supplied by OMIM, May 2004]
Chromosome	1
Cytoband	p36.22
Chromosome location (bp)	9997206 - 10016020
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162444 (version 83.38)
Entrez gene	116362
UniProt	Q96R05 (UniProt - Evidence at protein level)
neXtProt	NX_Q96R05
Antibodypedia	RBP7 antibodies

PROTEIN BROWSER

RBP7-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RBP7-001 ENSP00000294435 ENST00000294435	Q96R05 [Direct mapping] Retinoid-binding protein 7 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005501 [retinoid binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0016918 [retinal binding] GO:0019841 [retinol binding] Show all	134 aa 15.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.