Cell atlas - TSSK3 - The Human Protein Atlas

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TSSK3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear bodies
	Nucleoli
	Nucleus

Human cell
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	TSSK3
Gene description	Testis-specific serine kinase 3
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleus & nucleoli. In addition localized to the nuclear bodies.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved), Nucleoli (approved)
Additional location	In addition localized to the Nuclear bodies (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA037516
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleus & nucleoli. In addition localized to the nuclear bodies.

Main location

Nucleus (approved), Nucleoli (approved)

Additional location

Nuclear bodies (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA037516	HeLa	Nucleus
			Nucleoli
			Nuclear bodies
	HPA037516	SK-MEL-30	Nucleus
			Nucleoli
			Nuclear bodies	Intensity
	HPA037516	U-2 OS	Nucleus
	HPA037516	U-2 OS	Nucleoli

GENE INFORMATION
Gene name	TSSK3 (HGNC Symbol)
Synonyms	SPOGA3, STK22C
Description	Testis-specific serine kinase 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a kinase expressed exclusively in the testis that is thought to play a role in either germ cell differentiation or mature sperm function. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p35.1
Chromosome location (bp)	32351521 - 32364312
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162526 (version 83.38)
Entrez gene	81629
UniProt	Q96PN8 (UniProt - Evidence at protein level)
neXtProt	NX_Q96PN8
Antibodypedia	TSSK3 antibodies

PROTEIN BROWSER

TSSK3-001	TSSK3-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TSSK3-001 ENSP00000362634 ENST00000373534	Q96PN8 [Direct mapping] Testis-specific serine/threonine-protein kinase 3 Show all	Enzymes ENZYME proteins Transferases Kinases CAMK Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000287 [magnesium ion binding] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] GO:0007275 [multicellular organismal development] GO:0007283 [spermatogenesis] GO:0030154 [cell differentiation] GO:0035556 [intracellular signal transduction] Show all	268 aa 30.1 kDa	No	0
TSSK3-002 ENSP00000459187 ENST00000574315	I3L1X4 [Direct mapping] Testis-specific serine/threonine-protein kinase 3 Show all	Predicted intracellular proteins Show all	GO:0004674 [protein serine/threonine kinase activity] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] GO:0035556 [intracellular signal transduction] Show all	35 aa 3.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.