Expression of MEGF6 in cancer - Summary

CANCER ATLAS

Gene description

Multiple EGF-like-domains 6

Protein class

Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA052129

GENE INFORMATION
Gene name	MEGF6 (HGNC Symbol)
Synonyms	EGFL3
Description	Multiple EGF-like-domains 6 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p36.32
Chromosome location (bp)	3489920 - 3611495
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162591 (version 83.38)
Entrez gene	1953
UniProt	O75095 (UniProt - Evidence at protein level)
neXtProt	NX_O75095
Antibodypedia	MEGF6 antibodies

PROTEIN BROWSER

MEGF6-001	MEGF6-005	MEGF6-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MEGF6-001 ENSP00000294599 ENST00000294599	O75095 [Direct mapping] Multiple epidermal growth factor-like domains protein 6 Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005576 [extracellular region] GO:0008150 [biological_process] Show all	1229 aa 128.6 kDa	Yes	0
MEGF6-005 ENSP00000420386 ENST00000491842	H7C5N9 [Direct mapping] Multiple epidermal growth factor-like domains protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	248 aa 25.4 kDa	No	0
MEGF6-007 ENSP00000348982 ENST00000356575	O75095 [Direct mapping] Multiple epidermal growth factor-like domains protein 6 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005576 [extracellular region] GO:0008150 [biological_process] Show all	1541 aa 161.2 kDa	Yes	0