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ZNF281

CANCER ATLAS

Gene description

 Zinc finger protein 281

Protein class

 Predicted intracellular proteins, Transcription factors

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA051228

GENE INFORMATION

Gene name

 ZNF281 (HGNC Symbol)

Synonyms

 ZBP-99

Description

 Zinc finger protein 281 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q32.1

Chromosome location (bp)

 200404940 - 200410056

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000162702 (version 83.38)

Entrez gene

 23528

UniProt

 Q9Y2X9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y2X9

Antibodypedia

 ZNF281 antibodies

PROTEIN BROWSER
ZNF281-001
ZNF281-002
ZNF281-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZNF281-001
ENSP00000294740
ENST00000294740
Q9Y2X9 [Direct mapping]
Zinc finger protein 281
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001047 [core promoter binding]
GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0010172 [embryonic body morphogenesis]
GO:0010629 [negative regulation of gene expression]
GO:0043565 [sequence-specific DNA binding]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:0048863 [stem cell differentiation]
Show all
 895 aa
96.9 kDa 		No 0
ZNF281-002
ENSP00000356322
ENST00000367353
Q9Y2X9 [Direct mapping]
Zinc finger protein 281
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001047 [core promoter binding]
GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0010172 [embryonic body morphogenesis]
GO:0010629 [negative regulation of gene expression]
GO:0043565 [sequence-specific DNA binding]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:0048863 [stem cell differentiation]
Show all
 895 aa
96.9 kDa 		No 0
ZNF281-003
ENSP00000356321
ENST00000367352
Q9Y2X9 [Direct mapping]
Zinc finger protein 281
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001047 [core promoter binding]
GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0010172 [embryonic body morphogenesis]
GO:0010629 [negative regulation of gene expression]
GO:0043565 [sequence-specific DNA binding]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:0048863 [stem cell differentiation]
Show all
 859 aa
93.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.