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A majority of cancer cells displayed moderate cytoplasmic positivity. Papillary adenocarcinomas of thyroid along a few cases of prostate and ovarian cancers were strongly stained. Most liver, renal, endometrial and gastric cancers were weakly stained or negative.
Most cancer tissues exhibited moderate cytoplasmic immunoreactivity. Additional nuclear/nucleolar positivity was displayed in gliomas and few prostate cancers. Few stomach cancers and squamous cell carcinomas of skin showed additional membranous positivity. Papillary adenocarcinomas of thyroid along with few seminomas, prostate and pancreatic cancers were strongly stained.
GENE INFORMATION
Gene name
PPP1R21 (HGNC Symbol)
Synonyms
CCDC128, FLJ16566, KLRAQ1
Description
Protein phosphatase 1, regulatory subunit 21 (HGNC Symbol)