Expression of LRRTM1 in cancer - Summary

CANCER ATLAS

Gene description

Leucine rich repeat transmembrane neuronal 1

Protein class

Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA062660

GENE INFORMATION
Gene name	LRRTM1 (HGNC Symbol)
Synonyms	FLJ32082
Description	Leucine rich repeat transmembrane neuronal 1 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p12
Chromosome location (bp)	80288351 - 80304749
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000162951 (version 83.38)
Entrez gene	347730
UniProt	Q86UE6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q86UE6
Antibodypedia	LRRTM1 antibodies

PROTEIN BROWSER

LRRTM1-002	LRRTM1-003	LRRTM1-004	LRRTM1-005	LRRTM1-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LRRTM1-002 ENSP00000295057 ENST00000295057	Q86UE6 [Direct mapping] Leucine-rich repeat transmembrane neuronal protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0002091 [negative regulation of receptor internalization] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0007626 [locomotory behavior] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0030424 [axon] GO:0030426 [growth cone] GO:0035418 [protein localization to synapse] GO:0035640 [exploration behavior] GO:0045211 [postsynaptic membrane] GO:0050808 [synapse organization] GO:0051965 [positive regulation of synapse assembly] GO:0060076 [excitatory synapse] GO:0060291 [long-term synaptic potentiation] Show all	522 aa 58.6 kDa	Yes	1
LRRTM1-003 ENSP00000404557 ENST00000415098	C9JF97 [Direct mapping] Leucine-rich repeat transmembrane neuronal protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] Show all	109 aa 12.1 kDa	Yes	0
LRRTM1-004 ENSP00000415368 ENST00000416268	C9JEE2 [Direct mapping] Leucine-rich repeat transmembrane neuronal protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] Show all	223 aa 25.3 kDa	Yes	0
LRRTM1-005 ENSP00000389473 ENST00000452811	C9JPM9 [Direct mapping] Leucine-rich repeat transmembrane neuronal protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] Show all	183 aa 20.7 kDa	Yes	0
LRRTM1-007 ENSP00000386646 ENST00000409148	Q86UE6 [Direct mapping] Leucine-rich repeat transmembrane neuronal protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0030424 [axon] GO:0030426 [growth cone] GO:0045211 [postsynaptic membrane] Show all	522 aa 58.6 kDa	Yes	1