We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
A majority of malignant cells displayed moderate to strong cytoplasmic positivity. Malignant gliomas, lymphomas, urothelial and renal cancers were in general weakly stained or negative.
Few cases of colorectal, prostate, renal cancers and malignant lymphomas showed moderate cytoplasmic positivity. Remaining malignancies were weakly stained or negative.
GENE INFORMATION
Gene name
KCNF1 (HGNC Symbol)
Synonyms
IK8, KCNF, kH1, Kv5.1
Description
Potassium channel, voltage gated modifier subfamily F, member 1 (HGNC Symbol)
Entrez gene summary
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008]
