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Cancer tissues displayed moderate to strong cytoplasmic positivity with additional membranous staining in several cases. Most cases of prostate cancers were weakly stained.
Most malignant tissues showed weak to moderate cytoplasmic and/or nucleolar staining. Malignant carcinoids, malignant gliomas along with several malignant lymphomas were negative.
GENE INFORMATION
Gene name
CCDC140 (HGNC Symbol)
Synonyms
FLJ32447
Description
Coiled-coil domain containing 140 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that appears to be restricted to select higher primate species. This protein contains a C-terminal coiled-coil domain, which is a versatile structural motif consisting of multiple amphipathic alpha-helices that twist around each other to form a supercoil. [provided by RefSeq, Aug 2011]
