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Most cancers exhibited moderate to strong cytoplasmic immunoreactivity with additional membranous staining in several cases. Gliomas, lymphomas, basal cell carcinomas, prostate and testicular cancers were generally negative.
GENE INFORMATION
Gene name
SCNM1 (HGNC Symbol)
Synonyms
MGC3180
Description
Sodium channel modifier 1 (HGNC Symbol)
Entrez gene summary
SCNM1 is a zinc finger protein and putative splicing factor. In mice, Scnm1 modifies phenotypic expression of Scn8a (MIM 600702) mutations (Buchner et al., 2003 [PubMed 12920299]).[supplied by OMIM, Oct 2009]