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Several liver and prostate cancers along with a few melanomas, breast, colorectal, endometrial, stomach and pancreatic cancers displayed weak to moderate cytoplasmic positivity. Remaining tumour cells were negative.
GENE INFORMATION
Gene name
FZD5 (HGNC Symbol)
Synonyms
C2orf31, DKFZP434E2135, HFZ5
Description
Frizzled class receptor 5 (HGNC Symbol)
Entrez gene summary
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008]