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Moderate to strong membranous staining with occasional cytoplasmic and nuclear immunoreactivity was observed in several colorectal and ovarian cancers along with a few malignant melanomas, skin, liver, stomach, urothelial and pancreatic cancers. Most remaining malignant cells were weakly stained or negative.
GENE INFORMATION
Gene name
YY1AP1 (HGNC Symbol)
Synonyms
HCCA2, YAP, YY1AP
Description
YY1 associated protein 1 (HGNC Symbol)
Entrez gene summary
The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]