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Moderate cytoplasmic staining was observed in most malignancies. Several colorectal cancers along with cases of squamous cell carcinomas and ovarian cancers were strongly stained. Testicular cancers were negative.
GENE INFORMATION
Gene name
AZI2 (HGNC Symbol)
Synonyms
AZ2, FLJ21939, NAP1
Description
5-azacytidine induced 2 (HGNC Symbol)
Entrez gene summary
AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008]