Fields »
ABOUT
HELP
BLOG
CLASP2

GENERAL INFORMATION

Gene name

 CLASP2

Gene description

 Cytoplasmic linker associated protein 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 14
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (cerebral cortex)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CLASP2 (HGNC Symbol)

Synonyms

 KIAA0627

Description

 Cytoplasmic linker associated protein 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 p22.3

Chromosome location (bp)

 33496245 - 33718356

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163539 (version 83.38)

Entrez gene

 23122

UniProt

 O75122 (UniProt - Evidence at protein level)

neXtProt

 NX_O75122

Antibodypedia

 CLASP2 antibodies

PROTEIN BROWSER
«
CLASP2-001
CLASP2-002
CLASP2-003
CLASP2-006
CLASP2-007
CLASP2-008
CLASP2-010
CLASP2-018
CLASP2-021
CLASP2-023
CLASP2-024
CLASP2-025
CLASP2-026
CLASP2-201
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CLASP2-001
ENSP00000419974
ENST00000468888
E7EW49 [Direct mapping]
CLIP-associating protein 2
Show all
   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
 1514 aa
165.7 kDa 		No 0
CLASP2-002
ENSP00000382297
ENST00000399362
E7ERI8 [Direct mapping]
CLIP-associating protein 2
Show all
   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
 1513 aa
165.6 kDa 		No 0
CLASP2-003
ENSP00000417518
ENST00000480013
J3KR49 [Direct mapping]
CLIP-associating protein 2
Show all
   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0007026 [negative regulation of microtubule depolymerization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0016477 [cell migration]
Show all
 1293 aa
140.9 kDa 		No 0
CLASP2-006
ENSP00000418939
ENST00000487200
B3KR06 [Direct mapping]
CLIP-associating protein 2; Cytoplasmic linker associated protein 2, isoform CRA_c; cDNA FLJ33397 fis, clone BRACE2007937, highly similar to CLIP-associating protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
 454 aa
49.2 kDa 		No 0
CLASP2-007
ENSP00000324364
ENST00000313350
O75122 [Direct mapping]
CLIP-associating protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0000777 [condensed chromosome kinetochore]
GO:0002162 [dystroglycan binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005815 [microtubule organizing center]
GO:0005828 [kinetochore microtubule]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005881 [cytoplasmic microtubule]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006903 [vesicle targeting]
GO:0007020 [microtubule nucleation]
GO:0007026 [negative regulation of microtubule depolymerization]
GO:0007030 [Golgi organization]
GO:0007052 [mitotic spindle organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007411 [axon guidance]
GO:0008017 [microtubule binding]
GO:0010458 [exit from mitosis]
GO:0010470 [regulation of gastrulation]
GO:0010634 [positive regulation of epithelial cell migration]
GO:0010717 [regulation of epithelial to mesenchymal transition]
GO:0016020 [membrane]
GO:0030516 [regulation of axon extension]
GO:0031023 [microtubule organizing center organization]
GO:0031110 [regulation of microtubule polymerization or depolymerization]
GO:0031113 [regulation of microtubule polymerization]
GO:0031252 [cell leading edge]
GO:0032587 [ruffle membrane]
GO:0032886 [regulation of microtubule-based process]
GO:0032956 [regulation of actin cytoskeleton organization]
GO:0034453 [microtubule anchoring]
GO:0035791 [platelet-derived growth factor receptor-beta signaling pathway]
GO:0044295 [axonal growth cone]
GO:0045180 [basal cortex]
GO:0045921 [positive regulation of exocytosis]
GO:0051010 [microtubule plus-end binding]
GO:0051015 [actin filament binding]
GO:0051301 [cell division]
GO:0051497 [negative regulation of stress fiber assembly]
GO:0051895 [negative regulation of focal adhesion assembly]
GO:0072686 [mitotic spindle]
GO:0090002 [establishment of protein localization to plasma membrane]
GO:0090091 [positive regulation of extracellular matrix disassembly]
GO:1903690 [negative regulation of wound healing, spreading of epidermal cells]
GO:1903754 [cortical microtubule plus-end]
GO:1904261 [positive regulation of basement membrane assembly involved in embryonic body morphogenesis]
GO:1990782 [protein tyrosine kinase binding]
Show all
 431 aa
46.5 kDa 		No 0
CLASP2-008
ENSP00000327760
ENST00000333778
E7ENG2 [Direct mapping]
CLIP-associating protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
 458 aa
49.6 kDa 		No 0
CLASP2-010
ENSP00000419305
ENST00000461133
E3W994 [Direct mapping]
CLIP-associating protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
 1273 aa
138.9 kDa 		No 0
CLASP2-018
ENSP00000420307
ENST00000487553
H7C5M8 [Direct mapping]
CLIP-associating protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
 220 aa
24.8 kDa 		No 0
CLASP2-021
ENSP00000417386
ENST00000480385
H7C4I5 [Direct mapping]
CLIP-associating protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
 205 aa
22.5 kDa 		No 0
CLASP2-023
ENSP00000417666
ENST00000475576
H7C4M5 [Direct mapping]
CLIP-associating protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 179 aa
19.3 kDa 		No 0
CLASP2-024
ENSP00000418411
ENST00000496954
C9J668 [Direct mapping]
CLIP-associating protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 178 aa
18.9 kDa 		No 0
CLASP2-025
ENSP00000418945
ENST00000485378
D6RBU8 [Direct mapping]
CLIP-associating protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
 233 aa
25.2 kDa 		No 0
CLASP2-026
ENSP00000489023
ENST00000635664
   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
 1304 aa
142.3 kDa 		No 0
CLASP2-201
ENSP00000352581
ENST00000359576
O75122 [Direct mapping]
CLIP-associating protein 2
Show all
   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0000777 [condensed chromosome kinetochore]
GO:0002162 [dystroglycan binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005815 [microtubule organizing center]
GO:0005828 [kinetochore microtubule]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005881 [cytoplasmic microtubule]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006903 [vesicle targeting]
GO:0007020 [microtubule nucleation]
GO:0007026 [negative regulation of microtubule depolymerization]
GO:0007030 [Golgi organization]
GO:0007052 [mitotic spindle organization]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007411 [axon guidance]
GO:0008017 [microtubule binding]
GO:0010458 [exit from mitosis]
GO:0010470 [regulation of gastrulation]
GO:0010634 [positive regulation of epithelial cell migration]
GO:0010717 [regulation of epithelial to mesenchymal transition]
GO:0016020 [membrane]
GO:0030516 [regulation of axon extension]
GO:0031023 [microtubule organizing center organization]
GO:0031110 [regulation of microtubule polymerization or depolymerization]
GO:0031113 [regulation of microtubule polymerization]
GO:0031252 [cell leading edge]
GO:0032587 [ruffle membrane]
GO:0032886 [regulation of microtubule-based process]
GO:0032956 [regulation of actin cytoskeleton organization]
GO:0034453 [microtubule anchoring]
GO:0035791 [platelet-derived growth factor receptor-beta signaling pathway]
GO:0044295 [axonal growth cone]
GO:0045180 [basal cortex]
GO:0045921 [positive regulation of exocytosis]
GO:0051010 [microtubule plus-end binding]
GO:0051015 [actin filament binding]
GO:0051301 [cell division]
GO:0051497 [negative regulation of stress fiber assembly]
GO:0051895 [negative regulation of focal adhesion assembly]
GO:0072686 [mitotic spindle]
GO:0090002 [establishment of protein localization to plasma membrane]
GO:0090091 [positive regulation of extracellular matrix disassembly]
GO:1903690 [negative regulation of wound healing, spreading of epidermal cells]
GO:1903754 [cortical microtubule plus-end]
GO:1904261 [positive regulation of basement membrane assembly involved in embryonic body morphogenesis]
GO:1990782 [protein tyrosine kinase binding]
Show all
 1515 aa
165.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.