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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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PCOLCE2
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CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Procollagen C-endopeptidase enhancer 2

Protein class

Predicted secreted proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA013203

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most cancers showed moderate to strong cytoplasmic staining. Gliomas, lymphomas and testicular cancers were generally negative.

GENE INFORMATION

Gene name

PCOLCE2 (HGNC Symbol)

Synonyms

PCPE2

Description

Procollagen C-endopeptidase enhancer 2 (HGNC Symbol)

Entrez gene summary

Chromosome

3

Cytoband

q23

Chromosome location (bp)

142815922 - 142889203

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163710 (version 83.38)

Entrez gene

26577

UniProt

Q9UKZ9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UKZ9

Antibodypedia

PCOLCE2 antibodies

PROTEIN BROWSER

PCOLCE2-001
PCOLCE2-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PCOLCE2-001
ENSP00000295992
ENST00000295992
Q9UKZ9 [Direct mapping]
Procollagen C-endopeptidase enhancer 2
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005518 [collagen binding]
GO:0008201 [heparin binding]
GO:0010952 [positive regulation of peptidase activity]
GO:0016504 [peptidase activator activity]
GO:0070062 [extracellular exosome]
Show all
415 aa
45.7 kDa
Yes 0
PCOLCE2-004
ENSP00000419842
ENST00000485766
C9JYX9 [Direct mapping]
Procollagen C-endopeptidase enhancer 2
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
303 aa
33.8 kDa
Yes 0

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