Cell atlas - CXCL3 - The Human Protein Atlas

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CXCL3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CXCL3
Gene description	Chemokine (C-X-C motif) ligand 3
Protein class	Plasma proteins Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (BJ hTERT+, RPTEC TERT1)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (BJ hTERT+, RPTEC TERT1) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CXCL3 (HGNC Symbol)
Synonyms	CINC-2b, GRO3, GROg, MIP-2b, SCYB3
Description	Chemokine (C-X-C motif) ligand 3 (HGNC Symbol)
Entrez gene summary	This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014]
Chromosome	4
Cytoband	q13.3
Chromosome location (bp)	74036589 - 74038807
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163734 (version 83.38)
Entrez gene	2921
UniProt	P19876 (UniProt - Evidence at protein level)
neXtProt	NX_P19876
Antibodypedia	CXCL3 antibodies

PROTEIN BROWSER

CXCL3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CXCL3-001 ENSP00000296026 ENST00000296026	P19876 [Direct mapping] C-X-C motif chemokine 3 GRO-gamma(5-73) Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Show all	GO:0002690 [positive regulation of leukocyte chemotaxis] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0006954 [inflammatory response] GO:0006955 [immune response] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008009 [chemokine activity] GO:0030593 [neutrophil chemotaxis] GO:0032496 [response to lipopolysaccharide] GO:0042127 [regulation of cell proliferation] GO:0045236 [CXCR chemokine receptor binding] GO:0070098 [chemokine-mediated signaling pathway] Show all	107 aa 11.3 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.