Cell atlas - YEATS2 - The Human Protein Atlas

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YEATS2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	YEATS2
Gene description	YEATS domain containing 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA045891
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA045891	A-431	Nucleoplasm
	HPA045891	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	YEATS2 (HGNC Symbol)
Synonyms	FLJ10201, FLJ12841, FLJ13308, KIAA1197
Description	YEATS domain containing 2 (HGNC Symbol)
Entrez gene summary	YEATS2 is a scaffolding subunit of the ADA2A (TADA2A; MIM 602276)-containing (ATAC) histone acetyltransferase complex (Wang et al., 2008 [PubMed 18838386]).[supplied by OMIM, Apr 2010]
Chromosome	3
Cytoband	q27.1
Chromosome location (bp)	183697818 - 183812625
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163872 (version 83.38)
Entrez gene	55689
UniProt	Q9ULM3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9ULM3
Antibodypedia	YEATS2 antibodies

PROTEIN BROWSER

YEATS2-001	YEATS2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
YEATS2-001 ENSP00000306983 ENST00000305135	Q9ULM3 [Direct mapping] YEATS domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005671 [Ada2/Gcn5/Ada3 transcription activator complex] GO:0006325 [chromatin organization] GO:0006355 [regulation of transcription, DNA-templated] GO:0017025 [TBP-class protein binding] GO:0043966 [histone H3 acetylation] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0072686 [mitotic spindle] Show all	1422 aa 150.8 kDa	No	0
YEATS2-003 ENSP00000406477 ENST00000432781	H0Y6M6 [Direct mapping] YEATS domain-containing protein 2 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006355 [regulation of transcription, DNA-templated] Show all	219 aa 21.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.