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S100P

GENERAL INFORMATION

Gene name

 S100P

Gene description

 S100 calcium binding protein P

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (stomach, urinary bladder, bone marrow)
GTEx:Group enriched (urinary bladder, stomach, esophagus)
FANTOM5:Tissue enhanced (placenta, urinary bladder)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and nuclear expression mainly in bone marrow, placenta and glandular epithelia in several tissues, including stomach and urinary bladder.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending restaining.

Reliability score

 Supported based on 1 antibody.
HPA019502
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (stomach, urinary bladder, bone marrow)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (urinary bladder, stomach, esophagus)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (placenta, urinary bladder)

GENE INFORMATION

Gene name

 S100P

Synonyms

Description

 S100 calcium binding protein P (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008]

Chromosome

 4

Cytoband

 p16.1

Chromosome location (bp)

 6693069 - 6697170

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163993 (version 83.38)

Entrez gene

 6286

UniProt

 P25815 (UniProt - Evidence at protein level)

neXtProt

 NX_P25815

Antibodypedia

 S100P antibodies

PROTEIN BROWSER
S100P-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
S100P-001
ENSP00000296370
ENST00000296370
P25815 [Direct mapping]
Protein S100-P
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000287 [magnesium ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0010033 [response to organic substance]
GO:0031528 [microvillus membrane]
GO:0043542 [endothelial cell migration]
GO:0048306 [calcium-dependent protein binding]
GO:0050786 [RAGE receptor binding]
GO:0070062 [extracellular exosome]
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 95 aa
10.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.