Expression of GPX8 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Glutathione peroxidase 8 (putative)

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Stomach cancer

STAINING SUMMARY

HPA036720	HPA036721

GENE INFORMATION
Gene name	GPX8 (HGNC Symbol)
Synonyms	EPLA847, UNQ847
Description	Glutathione peroxidase 8 (putative) (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q11.2
Chromosome location (bp)	55160118 - 55167071
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164294 (version 83.38)
Entrez gene	493869
UniProt	Q8TED1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TED1
Antibodypedia	GPX8 antibodies

PROTEIN BROWSER

GPX8-001	GPX8-003	GPX8-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPX8-001 ENSP00000423822 ENST00000503787	Q8TED1 [Direct mapping] Probable glutathione peroxidase 8 Show all	Enzymes ENZYME proteins Oxidoreductases MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000302 [response to reactive oxygen species] GO:0004601 [peroxidase activity] GO:0004602 [glutathione peroxidase activity] GO:0005788 [endoplasmic reticulum lumen] GO:0006979 [response to oxidative stress] GO:0016021 [integral component of membrane] GO:0055114 [oxidation-reduction process] Show all	209 aa 23.9 kDa	No	0
GPX8-003 ENSP00000427466 ENST00000515370	E7ETY7 [Direct mapping] Glutathione peroxidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004602 [glutathione peroxidase activity] GO:0006979 [response to oxidative stress] GO:0055114 [oxidation-reduction process] Show all	158 aa 18.1 kDa	No	0
GPX8-004 ENSP00000296734 ENST00000296734	J3KNB5 [Direct mapping] Probable glutathione peroxidase 8 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004602 [glutathione peroxidase activity] GO:0006979 [response to oxidative stress] GO:0016021 [integral component of membrane] GO:0055114 [oxidation-reduction process] Show all	90 aa 10.1 kDa	No	0