Tissue expression of EBF1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	EBF1
Gene description	Early B-cell factor 1
Protein class	Cancer-related genes Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (adipose tissue)
GTEx:	Mixed
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (adipose tissue)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	EBF1 (HGNC Symbol)
Synonyms	EBF, OLF1
Description	Early B-cell factor 1 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q33.3
Chromosome location (bp)	158695916 - 159099761
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164330 (version 83.38)
Entrez gene	1879
UniProt	Q9UH73 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UH73
Antibodypedia	EBF1 antibodies

PROTEIN BROWSER

EBF1-001	EBF1-002	EBF1-006	EBF1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EBF1-001 ENSP00000322898 ENST00000313708	Q9UH73 [Direct mapping] Transcription factor COE1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Transcription factors Immunoglobulin fold Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Kim et al 2014) Show all	GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007275 [multicellular organismal development] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] GO:0046983 [protein dimerization activity] GO:0070742 [C2H2 zinc finger domain binding] Show all	591 aa 64.5 kDa	No	0
EBF1-002 ENSP00000370029 ENST00000380654	Q9UH73 [Direct mapping] Transcription factor COE1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Transcription factors Immunoglobulin fold Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007275 [multicellular organismal development] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] GO:0046983 [protein dimerization activity] Show all	560 aa 61.1 kDa	No	0
EBF1-006 ENSP00000428020 ENST00000517373	E5RFQ1 [Direct mapping] Transcription factor COE1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0046872 [metal ion binding] GO:0046983 [protein dimerization activity] Show all	523 aa 57.5 kDa	No	0
EBF1-201 ENSP00000477809 ENST00000622875	A0A087WTE5 [Direct mapping] Transcription factor COE1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0006355 [regulation of transcription, DNA-templated] Show all	407 aa 43.8 kDa	No	0